Evidence map›Paper›PMID 23752663›Full record

ArticleAnnals of internal medicine2013

Brand-name prescription drug use among Veterans Affairs and Medicare Part D patients with diabetes: a national cohort comparison.

Walid F Gellad, Julie M Donohue, Xinhua Zhao, Maria K Mor, Carolyn T Thorpe, Jeremy Smith, Chester B Good, Michael J Fine, Nancy E Morden

Open access · greenAbstract readComparative Study
In one paragraph

Article in Annals of internal medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
25.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Influencers of generic drug utilization: A systematic review.Research in social & administrative pharmacy : RSAP · 2018
    Pooled it
  2. Pooled it
  3. Comparing VA and Non-VA Quality of Care: A Systematic Review.Journal of general internal medicine · 2017
    Pooled it
  4. Review
  5. Article
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  16. Role of pharmacy services in accountable care organizations.Journal of managed care & specialty pharmacy · 2015
    Article
  17. Article
  18. Observational
  19. Teaching Wisely.Journal of graduate medical education · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Walid F GelladCenter for Health Equity Research and Promotion, Veterans Affairs Pittsburgh Healthcare System, 7180 Highland Drive, Pittsburgh, PA 15206, USA. walid.gellad@va.gov
Julie M Donohue
Xinhua Zhao
Maria K Mor
Carolyn T Thorpe
Jeremy Smith
Chester B Good
Michael J Fine
Nancy E Morden
Dartmouth College · USUnited States Department of Veterans Affairs · USUniversity of Pittsburgh · USVA Pittsburgh Healthcare System · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
UNDERSTANDING AND IMPROVING EPISODE-BASED HOSPITAL CAREP01AG019783 · NIA · DARTMOUTH COLLEGE · PI Leila S. Agha · 2001 to 2026
$52.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Impact of Medicare Part D on Racial Disparities in Diabetes Treatment and OutcomeR01HS017695 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONOHUE, JULIE MARIE · 2009 to 2011
$628k
The Risk of Polypharmacy-related Fracture in Older AdultsK23AG035030 · NIA · DARTMOUTH COLLEGE · PI MORDEN, NANCY E · 2011 to 2013
$416k
AHRQ HHS R01 HS017695AHRQ HHS R01HS017695HSRD VA CDA 09-207NCATS NIH HHS UL1 TR000005NCRR NIH HHS UL1 RR024153NIA NIH HHS K23 AG035030NIA NIH HHS P01 AG019783
6 · The paper itself

Abstract

backgroundMedicare Part D and the U.S. Department of Veterans Affairs (VA) use different approaches to manage prescription drug benefits, with implications for spending. Medicare relies on private plans with distinct formularies, whereas the VA administers its own benefit using a national formulary.

objectiveTo compare overall and regional rates of brand-name drug use among older adults with diabetes in Medicare and the VA.

designRetrospective cohort.

settingMedicare and the VA, 2008. PATIENTS: 1,061,095 Medicare Part D beneficiaries and 510,485 veterans aged 65 years or older with diabetes. MEASUREMENTS: Percentage of patients taking oral hypoglycemics, statins, and angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) who filled brand-name drug prescriptions and percentage of patients taking long-acting insulins who filled analogue prescriptions. Sociodemographic- and health status-adjusted hospital referral region (HRR) brand-name drug use was compared, and changes in spending were calculated if use of brand-name drugs in 1 system mirrored the other.

resultsBrand-name drug use in Medicare was 2 to 3 times that in the VA: 35.3% versus 12.7% for oral hypoglycemics, 50.7% versus 18.2% for statins, 42.5% versus 20.8% for ACE inhibitors or ARBs, and 75.1% versus 27.0% for insulin analogues. Adjusted HRR-level brand-name statin use ranged (from the 5th to 95th percentiles) from 41.0% to 58.3% in Medicare and 6.2% to 38.2% in the VA. For each drug group, the 95th-percentile HRR in the VA had lower brand-name drug use than the 5th-percentile HRR in Medicare. Medicare spending in this population would have been $1.4 billion less if brand-name drug use matched that of the VA. LIMITATION: This analysis cannot fully describe the factors underlying differences in brand-name drug use.

conclusionMedicare beneficiaries with diabetes use 2 to 3 times more brand-name drugs than a comparable group within the VA, at substantial excess cost.

Indexed as

AgedDiabetes MellitusDrugs, GenericFemaleHumansHypoglycemic AgentsMaleMedicare Part DPrescription DrugsRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsDrugs, GenericHypoglycemic AgentsPrescription Drugs

Identifiers

PMID23752663
PMCPMC3787067
OpenAlexW2080642151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.