Evidence map›Paper›PMID 23752513›Full record

ArticleAntimicrobial agents and chemotherapy2013

Complete sequences of two plasmids in a blaNDM-1-positive Klebsiella oxytoca isolate from Taiwan.

Tzu-Wen Huang, Jann-Tay Wang, Tsai-Ling Lauderdale, Tsai-Lien Liao, Jui-Fen Lai, Mei-Chen Tan, Ann-Chi Lin, Ying-Tsong Chen, Shih-Feng Tsai, Shan-Chwen Chang

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Emergence of carbapenem-resistantMicrobiology spectrum · 2025
    Article
  2. Article
  3. Comparative Genomics of an Emerging Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  4. Epidemiology, molecular characterization, and drug resistance of IncHI5 plasmids from Enterobacteriaceae.International microbiology : the official journal of the Spanish Society for Microbiology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Detection of IMP-4 and SFO-1 co-producing ST51Frontiers in cellular and infection microbiology · 2022
    Article
  10. Epidemiology ofInfection and drug resistance · 2022
    Article
  11. Article
  12. Article
  13. Carbapenemases: TransformingBiomolecules · 2020
    Review
  14. Article
  15. Review
  16. Characterization of blaEnvironmental science and pollution research international · 2019
    Article
  17. Coproduction Of MCR-9 And NDM-1 By Colistin-ResistantInfection and drug resistance · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tzu-Wen HuangInstitute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Taiwan.
Jann-Tay Wang
Tsai-Ling Lauderdale
Tsai-Lien Liao
Jui-Fen Lai
Mei-Chen Tan
Ann-Chi Lin
Ying-Tsong Chen
Shih-Feng Tsai
Shan-Chwen Chang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic determinants of a bla(NDM-1)-positive, multidrug-resistant bacterial isolate that caused active infection was investigated by DNA sequencing. Two plasmids, pKOX_NDM1 and pKOX-R1, were identified for the Klebsiella oxytoca strain E718. Sequence annotation revealed a bla(NDM-1) gene in pKOX_NDM1 and two extended-spectrum β-lactamase producers (bla(CTX-M-3) and blaSHV-12) and a wide array of resistance genes in pKOX-R1. These findings highlight the difficulty in treating multidrug-resistant bacterial infections and the potential danger of emerging resistant enterobacteria.

Indexed as

Genes, BacterialAminoglycosidesAnti-Bacterial Agentsbeta-LactamasesConjugation, GeneticEscherichia coliGenes, MDRHumansKlebsiella InfectionsKlebsiella oxytocaMicrobial Sensitivity TestsPlasmidsTaiwanAminoglycosidesAnti-Bacterial Agentsbeta-lactamase CTX-M-3beta-lactamase NDM-1beta-Lactamasesbeta-lactamase SHV-12

Identifiers

PMID23752513
PMCPMC3719732

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.