ArticleOncogene2014
The in vivo antitumor activity of cardiac glycosides in mice xenografted with human cancer cells is probably an experimental artifact.
Article in Oncogene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Repurposing acetyldigitoxin as a potential EZH2 inhibitor for non-small cell lung cancer: a computational and experimental approach.Journal of computer-aided molecular design · 2026Article
- Elucidating the Complex Structural and Molecular Mechanisms Driving P-Glycoprotein-Mediated Transport of Cardiac Glycosides.International journal of molecular sciences · 2025Article
- Plant glycosides and glycosidases: classification, sources, and therapeutic insights in current medicine.Glycoconjugate journal · 2025Review
- Molecular Basis of Na, K-ATPase Regulation of Diseases: Hormone and FXYD2 Interactions.International journal of molecular sciences · 2024Review
- Digoxin and its NaBioorganic & medicinal chemistry · 2024Review
- Anti-Trypanosomal Bufadienolides from the Oocytes of the ToadMolecules (Basel, Switzerland) · 2023Article
- Article
- Article
- Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma.International journal of molecular sciences · 2022Article
- Antiproliferative activity of cardenolides on cell line A549: structure-activity relationship analysis.Molecular diversity · 2021Article
- Screening for Selective Anticancer Activity of 65 Extracts of Plants Collected in Western Andalusia, Spain.Plants (Basel, Switzerland) · 2021Article
- Interaction of (+)-Strebloside and Its Derivatives with NaMolecules (Basel, Switzerland) · 2021Article
- Review
- Cardiac Glycosides as Immune System Modulators.Biomolecules · 2021Review
- Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity.Foods (Basel, Switzerland) · 2021Article
- Cardiac glycosides inhibit cancer through Na/K-ATPase-dependent cell death induction.Biochemical pharmacology · 2020Article
- Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL.Leukemia · 2020Article
- Potential Anticancer Agents Characterized from Selected Tropical Plants.Journal of natural products · 2019Review
- Proscillaridin A induces apoptosis and suppresses non-small-cell lung cancer tumor growth via calcium-induced DR4 upregulation.Cell death & disease · 2018Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.