Trial reportJournal of dental research2013
Patient stratification for preventive care in dentistry.
Trial report in Journal of dental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Periodontal Disease Prevention Study:A Retrospective Cohort Study to Assess the Effect of Genetics and Dental Preventive Care on Periodontal Disease
Engagement Study: (Multi-site, Practice-Based Research Network (PBRN) Prospective Clinical Trial to Assess if Knowledge of Genetic Risk Changes Behavior)
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Genetic Biomarkers for Periodontal Diseases: A Systematic Review.Journal of clinical periodontology · 2025Pooled it
- The Oral-Gut-Brain Axis: From Periodontal Dysbiosis to Neuroinflammation-Mechanistic Pathways, Salivary and Intestinal Biomarkers, and Therapeutic Targets: A Narrative Review.Dentistry journal · 2026Review
- Innovative Biomarkers for Oral Immunity: Advancements and Clinical Applications.Advances in experimental medicine and biology · 2026Review
- Innate Immunity Gene Variants Affect Periodontitis Susceptibility.Advances in experimental medicine and biology · 2026Article
- Machine learning-assisted prediction of clinical responses to periodontal treatment.Journal of periodontology · 2025Article
- The Precision Paradigm in Periodontology: A Multilevel Framework for Tailored Diagnosis, Treatment, and Prevention.Journal of personalized medicine · 2025Review
- Assessment of Trends in Non-Restorative and Preventative Dental Treatment Pre- and Post-COVID-19: A Health Informatics Pilot Study.Children (Basel, Switzerland) · 2025Article
- The importance of using interdental cleaning devices on prevention of tooth loss in an employee population: a cross-sectional study.BMC oral health · 2024Article
- Predicting oral hygiene practices through health behavior, perceived stress and self-efficacy in undergraduate dental students of Pakistan: a national survey.BMC oral health · 2024Article
- Exploring Interleukin Levels in Type 1 Diabetes and Periodontitis: A Review with a Focus on Childhood.Children (Basel, Switzerland) · 2024Review
- Medical, dental, and optical care utilization among community-living people with spinal cord injury in the United States.The journal of spinal cord medicine · 2024Article
- Integration of precision medicine into the dental care setting.Frontiers in dental medicine · 2024Article
- Applied artificial intelligence in dentistry: emerging data modalities and modeling approaches.Frontiers in artificial intelligence · 2024Review
- Genetic Control of GCF Exudation: Innate Immunity Genes and Periodontitis Susceptibility.International journal of molecular sciences · 2023Article
- Factors associated with scientific production citations in dentistry: Zero-inflated negative binomial regression and hurdle modelling.F1000Research · 2023Article
- Does preventive dental care reduce nonpreventive dental visits and expenditures among Medicaid-enrolled adults?Health services research · 2022Article
- Genomic Medicine in Periodontal Disease: Old Issue, New Insights.Journal of veterinary dentistry · 2022Article
- Article
- Review
- Risk factors and oral health-related quality of life: A case-control comparison between patients after a first-episode psychosis and people from general population.Journal of psychiatric and mental health nursing · 2022Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Prevention reduces tooth loss, but little evidence supports biannual preventive care for all adults. We used risk-based approaches to test tooth loss association with 1 vs. 2 annual preventive visits in high-risk (HiR) and low-risk (LoR) patients. Insurance claims for 16 years for 5,117 adults were evaluated retrospectively for tooth extraction events. Patients were classified as HiR for progressive periodontitis if they had ≥ 1 of the risk factors (RFs) smoking, diabetes, interleukin-1 genotype; or as LoR if no RFs. LoR event rates were 13.8% and 16.4% for 2 or 1 annual preventive visits (absolute risk reduction, 2.6%; 95%CI, 0.5% to 5.8%; p = .092). HiR event rates were 16.9% and 22.1% for 2 and 1 preventive visits (absolute risk reduction, 5.2%; 95%CI, 1.8% to 8.4%; p = .002). Increasing RFs increased events (p < .001). Oral health care costs were not increased by any single RF, regardless of prevention frequency (p > .41), but multiple RFs increased costs vs. no (p < .001) or 1 RF (p = .001). For LoR individuals, the association between preventive dental visits and tooth loss was not significantly different whether the frequency was once or twice annually. A personalized medicine approach combining gene biomarkers with conventional risk factors to stratify populations may be useful in resource allocation for preventive dentistry (ClinicalTrials.gov, NCT01584479).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.