Evidence map›Paper›PMID 23752096›Full record

ReviewNeuropharmacology2014

Amygdala and bed nucleus of the stria terminalis circuitry: Implications for addiction-related behaviors.

Alice M Stamatakis, Dennis R Sparta, Joshua H Jennings, Zoe A McElligott, Heather Decot, Garret D Stuber

Abstract readReview
In one paragraph

Review in Neuropharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Bed Nucleus of Stria Terminalis Enkephalin Neurons Contribute to Depletion-Induced Salt Appetite.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Distinct eLPBTheranostics · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alice M StamatakisDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neurobiology Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Dennis R Sparta
Joshua H Jennings
Zoe A McElligott
Heather Decot
Garret D Stuber

Funding

RESEARCH TRAINING IN THE NEUROSCIENCEST32NS007431 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Juan Song, Mark J. Zylka · 1997 to 2026
$10.0M
Supplement to Molecular and Cellular Studies on Alcohol's ActionsT32AA007573 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FULTON T CREWS, Thomas L. Kash · 1997 to 2026
$9.3M
Neural circuit elements that orchestrate cue-reward associationsR37DA032750 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Garret D Stuber · 2017 to 2026
$4.5M
Midbrain Neural Circuit Elements That Underlie Cue-Reward AssociationsR01DA032750 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STUBER, GARRET D · 2012 to 2016
$1.6M
Optogenetic control of excitatory synapses in the accumbens during behaviorR21DA029325 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STUBER, GARRET D · 2010 to 2011
$401k
Enhanced CRF Signaling in the VTA Following Binge DrinkingF32AA018610 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SPARTA, DENNIS R. · 2009 to 2011
$151k
Elucidating the Role of the LHb to VTA Circuit in Encoding Aversive BehaviorsF31DA034472 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STAMATAKIS, ALICE · 2012 to 2014
$102k
NIAAA NIH HHS AA007573NIAAA NIH HHS AA018610NIAAA NIH HHS F32 AA018610NIAAA NIH HHS T32 AA007573NIDA NIH HHS DA029325NIDA NIH HHS DA032750NIDA NIH HHS DA034472NIDA NIH HHS F31 DA034472NIDA NIH HHS R01 DA032750NIDA NIH HHS R21 DA029325NIDA NIH HHS R37 DA032750NINDS NIH HHS NS007431NINDS NIH HHS T32 NS007431
6 · The paper itself

Abstract

Complex motivated behavioral processes, such as those that can go awry following substance abuse and other neuropsychiatric disorders, are mediated by a distributive network of neurons that reside throughout the brain. Neural circuits within the amygdala regions, such as the basolateral amygdala (BLA), and downstream targets such as the bed nucleus of the stria terminalis (BNST), are critical neuroanatomical structures for orchestrating emotional behavioral responses that may influence motivated actions such as the reinstatement of drug seeking behavior. Here, we review the functional neurocircuitry of the BLA and the BNST, and discuss how these circuits may guide maladaptive behavioral processes such as those seen in addiction. Thus, further study of the functional connectivity within these brain regions and others may provide insight for the development of new treatment strategies for substance use disorders. This article is part of a Special Issue entitled 'NIDA 40th Anniversary Issue'.

Indexed as

AmygdalaAnimalsBehavior, AddictiveHumansNeural PathwaysSeptal NucleiAddictionAnxietyBasolateral amygdalaCircuitsExtended amygdalaPlasticityRewardStress

Identifiers

PMID23752096
PMCPMC3858407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.