Evidence map›Paper›PMID 23750465›Full record

Trial reportJournal of consulting and clinical psychology2013

Who gets the most out of cognitive behavioral therapy for anxiety disorders? The role of treatment dose and patient engagement.

Daniel Glenn, Daniela Golinelli, Raphael D Rose, Peter Roy-Byrne, Murray B Stein, Greer Sullivan, Alexander Bystritksy, Cathy Sherbourne, Michelle G Craske

3 registry-linked trialsAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 66 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00347269 phase4completednot on this map

Coordinated Anxiety Learning and Management (CALM): Improving Primary Care Anxiety Outcomes

TypeinterventionalSponsorUniversity of WashingtonRan2006 to 2009Enrolled1,004ConditionsPost-traumatic Stress Disorder, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety DisorderArmsCognitive-behavioral therapy, Psychotropic medication optimization, Treatment as Usual
NCT05019053 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Acceptability/Feasibility of COVID-19 Intervention of a Virtual Group Intervention for COVID-19 Distress

TypeinterventionalSponsorOhio UniversityRan2021 to 2022Enrolled24ConditionsSocial Isolation, Emotional DisorderArmsCoping Crew
NCT06604780 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Implementation and Evaluation of a Transition to Discharge Program for the Reduction of Early Readmission in a Mental Health Inpatient Unit

TypeinterventionalSponsorFundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludRan2023 to 2025Enrolled836ConditionsReadmission, Mental Health Disorder, Hospitalizations PsychiatricArmsTransitional discharge program
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  16. Preventing Childhood Anxiety Disorders: Is an Applied Game as Effective as a Cognitive Behavioral Therapy-Based Program?Prevention science : the official journal of the Society for Prevention Research · 2018
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel GlennDepartment of Psychology, University of California, Los Angeles.
Daniela GolinelliRAND Corporation.ORCID 0000-0002-6433-1752
Raphael D RoseDepartment of Psychology, University of California, Los Angeles.
Peter Roy-ByrneDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine.
Murray B SteinDepartments of Psychiatry and Family and Preventive Medicine, University of California, San Diego.
Greer SullivanSouth Central Veterans Affairs Mental Illness Research Education and Clinical Center.
Alexander BystritksyDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles.
Cathy SherbourneRAND Corporation.
Michelle G CraskeDepartment of Psychology, University of California, Los Angeles.

Funding

CALM: Improving Primary Care Anxiety OutcomesU01MH057835 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEIN, MURRAY B. · 2005 to 2009
$3.3M
CALM: IMPROVING PRIMARY CARE ANXIETY OUTCOMESU01MH070018 · NIMH · RAND CORPORATION · PI SHERBOURNE, CATHY D · 2005 to 2009
$3.1M
CALM: Improving Primary Care Anxiety OutcomesU01MH058915 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CRASKE, MICHELLE G · 2005 to 2009
$3.0M
CALM: Improving Primary Care OutcomesU01MH057858 · NIMH · UNIVERSITY OF WASHINGTON · PI ROY-BYRNE, PETER PAUL · 2005 to 2009
$2.4M
CALM: Improving Primary Care Anxiety OutcomesU01MH070022 · NIMH · UNIV OF ARKANSAS FOR MED SCIS · PI SULLIVAN, JAN GREER · 2005 to 2009
$2.3M
Improving Patient Outcomes in Anxiety DisordersK24MH064122 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEIN, MURRAY B. · 2001 to 2011
$1.3M
Treating Anxiety in Public Sector Medical SettingsK24MH065324 · NIMH · UNIVERSITY OF WASHINGTON · PI ROY-BYRNE, PETER PAUL · 2003 to 2007
$661k
NIMH NIH HHS K24 MH064122NIMH NIH HHS K24 MH065324NIMH NIH HHS K24 MH64122NIMH NIH HHS U01 MH057835NIMH NIH HHS U01MH057835NIMH NIH HHS U01 MH057858NIMH NIH HHS U01 MH058915NIMH NIH HHS U01 MH070018NIMH NIH HHS U01 MH070022
6 · The paper itself

Abstract

objectiveThe present study explored treatment dose and patient engagement as predictors of treatment outcome in cognitive behavioral therapy (CBT) for anxiety disorders.

methodMeasures of high versus low treatment dose and high versus low patient engagement in CBT were compared as predictors of 12- and 18-month outcomes for patients being treated for anxiety disorders with CBT (with or without concurrent pharmacotherapy) in primary care settings as part of a randomized controlled effectiveness trial of the Coordinated Anxiety Learning and Management (CALM) intervention. Measures of dose (attendance, exposure completion) and engagement in CBT (homework adherence, commitment) were collected throughout treatment, and blinded follow-up phone assessments of outcome measures (12-item Brief Symptom Inventory, Patient Health Questionnaire 8, Sheehan Disability Scale) were completed at 12 and 18 months. Propensity score weighting controlled for baseline differences in demographics and symptom severity between patients with high and low dose and engagement. These analyses included the 439 patients who selected CBT as treatment modality.

resultsCompleting exposures, having high attendance, and being more adherent to completing homework predicted better outcomes across all measures at 12 and 18 months, and high CBT commitment predicted better outcomes on all measures at 18 months.

conclusionsThis study found that higher treatment dose and patient engagement in CBT for anxiety disorders were stable and robust predictors of greater reductions in anxiety symptoms, depression symptoms, and functional disability.

Indexed as

Treatment OutcomeAdultAgedAnxiety DisordersCognitive Behavioral TherapyCombined Modality TherapyDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient CompliancePrognosisSingle-Blind Method

Identifiers

PMID23750465
PMCPMC3990403

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.