Evidence map›Paper›PMID 23750188›Full record

ArticleJournal of Parkinson's disease2013

Aerodynamic assessment of phonatory onset in Parkinson's disease: evidence of decreased scaling of laryngeal and respiratory control.

Michael J Hammer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Parkinson's disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Aerodynamic findings and Voice Handicap Index in Parkinson's disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael J HammerDepartment of Surgery, Division of Otolaryngology, University of Wisconsin, Madison, WI 53792, USA. hammer@surgery.wisc.edu
University of Wisconsin–Madison · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Institutional Clinical and Translational Science Award (UW-Madison)KL2RR025012 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$11.1M
Training & Education:Advanced Multidisciplinary Clinical Research (TEAM) (RMI)K12RR023268 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI CARNES, MOLLY L · 2005 to 2007
$6.3M
Does Intensive Voice Therapy Improve Airway Protection in Parkinsons DiseaseR03DC010900 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI HAMMER, MICHAEL J · 2010 to 2012
$436k
NCATS NIH HHS UL1 TR000427NCRR NIH HHS K12 RR023268NCRR NIH HHS KL2 RR025012NCRR NIH HHS RR023268NCRR NIH HHS RR025012NIDCD NIH HHS DC010900NIDCD NIH HHS L30 DC010356NIDCD NIH HHS R03 DC010900
6 · The paper itself

Abstract

backgroundPhonatory onset is important for speech and voice and may be substantially impaired in people with Parkinson's Disease (PD). However, the physiologic contributions of laryngeal and respiratory control to phonatory onset in PD are not well understood. Acoustic measurement of phonatory onset in neurological disease has been limited due to the confounding effects of dysarthria and the limited yield of physiologic detail.

objectiveThe purpose of this study was to test whether air flow measures would be useful to characterize respiratory and laryngeal contributions to phonatory onset, whether acoustic and air flow measures of phonatory onset were aberrant in PD, and whether deficits were significantly associated with voice severity.

methodsTwenty-one PD participants were tested and compared with 25 healthy controls. Testing included acoustic and air flow measures of phonatory onset during syllable production ([pa]) and measures of voice severity.

resultsAir flow assessment was possible for all participants; acoustic assessment was only possible for 86% of PD participants. Air flow and acoustic measures revealed shorter phonatory onset times for PD participants than controls. Air flow measures also revealed that PD participants expelled less lung air volume per syllable. Aberrant timing of phonatory onset and reduced lung air volume were associated with increased voice severity.

conclusionsThese findings suggest that air flow measures may be useful to assess the laryngeal and respiratory contributions to phonatory onset. These results also suggest that both respiratory and laryngeal control deficits may contribute to phonatory errors in PD, and that phonatory onset deficits are associated with voice severity.

Indexed as

AgedAnalysis of VarianceDiagnosis, Computer-AssistedFemaleFourier AnalysisHumansLaryngeal DiseasesLung Volume MeasurementsMaleNeurologic ExaminationParkinson DiseasePhonationRespiration DisordersSeverity of Illness IndexSpeech Production MeasurementTime Factorsacousticair flowlarynxSpeechvoicevolume

Identifiers

PMID23750188
PMCPMC3673725
OpenAlexW1568441342

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.