ArticleFrontiers in plant science2013
Iron biofortification of myanmar rice.
Article in Frontiers in plant science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 87 citations in OpenAlex.
- Crops and rising atmospheric COPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Improving Rice Grain Quality Through Ecotype Breeding for Enhancing Food and Nutritional Security in Asia-Pacific Region.Rice (New York, N.Y.) · 2024Review
- Simultaneous Enhancement of iron Deficiency Tolerance and Iron Accumulation in Rice by Combining the Knockdown of OsHRZ Ubiquitin Ligases with the Introduction of Engineered Ferric-chelate Reductase.Rice (New York, N.Y.) · 2022Article
- A tale of two metals: Biofortification of rice grains with iron and zinc.Frontiers in plant science · 2022Review
- Integrated breeding approaches to enhance the nutritional quality of food legumes.Frontiers in plant science · 2022Review
- Research and Progress on the Mechanism of Iron Transfer and Accumulation in Rice Grains.Plants (Basel, Switzerland) · 2021Review
- Improvement of nutrient use efficiency in rice: current toolbox and future perspectives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Review
- Iron Biofortification of Staple Crops: Lessons and Challenges in Plant Genetics.Plant & cell physiology · 2019Review
- Biotechnological Approaches for Generating Zinc-Enriched Crops to Combat Malnutrition.Nutrients · 2019Review
- Genetic Biofortification to Enrich Rice and Wheat Grain Iron: From Genes to Product.Frontiers in plant science · 2019Review
- Nicotianamine Synthesis byFrontiers in plant science · 2019Article
- Dealing with iron metabolism in rice: from breeding for stress tolerance to biofortification.Genetics and molecular biology · 2017Article
- Enhanced Grain Iron Levels in Rice Expressing anFrontiers in plant science · 2017Article
- NOD promoter-controlled AtIRT1 expression functions synergistically with NAS and FERRITIN genes to increase iron in rice grains.Plant molecular biology · 2016Article
- Rice grain nutritional traits and their enhancement using relevant genes and QTLs through advanced approaches.SpringerPlus · 2016Review
- Plant ferritin--a source of iron to prevent its deficiency.Nutrients · 2015Review
- Enriching rice with Zn and Fe while minimizing Cd risk.Frontiers in plant science · 2015Review
- miRNA regulation of nutrient homeostasis in plants.Frontiers in plant science · 2015Review
- Differential analysis of protein expression in RNA-binding-protein transgenic and parental rice seeds cultivated under salt stress.Journal of proteome research · 2014Article
- Iron biofortification of rice using different transgenic approaches.Rice (New York, N.Y.) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron (Fe) deficiency elevates human mortality rates, especially in developing countries. In Myanmar, the prevalence of Fe-deficient anemia in children and pregnant women are 75 and 71%, respectively. Myanmar people have one of the highest per capita rice consumption rates globally. Consequently, production of Fe-biofortified rice would likely contribute to solving the Fe-deficiency problem in this human population. To produce Fe-biofortified Myanmar rice by transgenic methods, we first analyzed callus induction and regeneration efficiencies in 15 varieties that are presently popular because of their high-yields or high-qualities. Callus formation and regeneration efficiency in each variety was strongly influenced by types of culture media containing a range of 2,4-dichlorophenoxyacetic acid concentrations. The Paw San Yin variety, which has a high-Fe content in polished seeds, performed well in callus induction and regeneration trials. Thus, we transformed this variety using a gene expression cassette that enhanced Fe transport within rice plants through overexpression of the nicotianamine synthase gene HvNAS1, Fe flow to the endosperm through the Fe(II)-nicotianamine transporter gene OsYSL2, and Fe accumulation in endosperm by the Fe storage protein gene SoyferH2. A line with a transgene insertion was successfully obtained. Enhanced expressions of the introduced genes OsYSL2, HvNAS1, and SoyferH2 occurred in immature T2 seeds. The transformants accumulated 3.4-fold higher Fe concentrations, and also 1.3-fold higher zinc concentrations in T2 polished seeds compared to levels in non-transgenic rice. This Fe-biofortified rice has the potential to reduce Fe-deficiency anemia in millions of Myanmar people without changing food habits and without introducing additional costs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.