Evidence map›Paper›PMID 23750044›Full record

ArticleCroatica chemica acta. Arhiv za kemiju2013

Lack of discrimination against non-proteinogenic amino acid norvaline by elongation factor Tu from

Nevena Cvetesic, Irena Akmacic, Ita Gruic-Sovulj

Open access · diamondAbstract read
In one paragraph

Article in Croatica chemica acta. Arhiv za kemiju, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Norvaline and norleucine may have been more abundant protein components during early stages of cell evolution.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nevena CvetesicDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Irena Akmacic
Ita Gruic-Sovulj
University of Zagreb · HR

Funding

Mechanism of proofreading by class I aminoacyl-tRNA synthetasesR03TW008024 · FIC · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI PERONA, JOHN J. · 2008 to 2010
$105k
FIC NIH HHS R03 TW008024
6 · The paper itself

Abstract

The GTP-bound form of elongation factor Tu (EF-Tu) brings aminoacylated tRNAs (aa-tRNA) to the A-site of the ribosome. EF-Tu binds all cognate elongator aa-tRNAs with highly similar affinities, and its weaker or tighter binding of misacylated tRNAs may discourage their participation in translation. Norvaline (Nva) is a non-proteinogenic amino acid that is activated and transferred to tRNA

Indexed as

aminoacyl-tRNA synthetasesEF-Tuleucyl-tRNA synthetasemistranslationnon-proteinogenic amino acidsnorvaline

Identifiers

PMID23750044
PMCPMC3675784
OpenAlexW2108465110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.