Trial reportWorld journal of urology2014
Prospective and randomized comparison of electrical stimulation of the posterior tibial nerve versus oxybutynin versus their combination for treatment of women with overactive bladder syndrome.
Trial report in World journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Home and outpatient electrostimulation in the treatment of urinary incontinence in women: a systematic review.BMC women's health · 2025Pooled it
- Conservative interventions for treating urinary incontinence in women: an Overview of Cochrane systematic reviews.The Cochrane database of systematic reviews · 2022Pooled it
- Pooled it
- Electrical stimulation with non-implanted electrodes for overactive bladder in adults.The Cochrane database of systematic reviews · 2016Pooled it
- Cholinergic Antagonists Combined with Electrical Stimulation or Bladder Training Treatments for Overactive Bladder in Female Adults: A Meta-Analysis of Randomized Controlled Trials.Clinical drug investigation · 2016Pooled it
- Comparative efficacy of transcutaneous tibial nerve stimulation (TTNS) versus solifenacin in female patients with overactive bladder.BMC urology · 2026Trial
- Randomized trial of transcutaneous tibial nerve stimulation to treat overactive bladder in older women.PloS one · 2026Trial
- Tibial nerve stimulation compared with sham to reduce incontinence in care home residents: ELECTRIC RCT.Health technology assessment (Winchester, England) · 2021Trial
- Effectiveness and durability of solifenacin versus percutaneous tibial nerve stimulation versus their combination for the treatment of women with overactive bladder syndrome: a randomized controlled study with a follow-up of ten months.International braz j urol : official journal of the Brazilian Society of UrologyTrial
- Impact of Urethral Sphincter Electrophysiology on Botulinum Toxin A Treatment in Women with Non-Neurogenic Dysfunctional Voiding.Biomedicines · 2024Article
- Updates in pelvic neuromodulation: the role of pelvic neuromodulation in pelvic disorders.Frontiers in urology · 2024Review
- Feasibility and acceptability of transcutaneous tibial nerve stimulation for the treatment of bladder storage symptoms among people with multiple sclerosis.Pilot and feasibility studies · 2022Article
- Randomized clinical trials assessing third-line therapies to treat non-neurogenic overactive bladder syndrome: a review about methodology.International urogynecology journal · 2021Review
- Do we need more patient-friendly treatment options for overactive bladder (OAB)?Neurourology and urodynamics · 2021Review
- Article
- Posterior tibial nerve stimulation for overactive bladder-techniques and efficacy.International urogynecology journal · 2020Article
- Electrostimulation of the posterior tibial nerve in individuals with overactive bladder: a literature review.Journal of physical therapy science · 2018Review
- Transcutaneous tibial nerve stimulation: 2 years follow-up outcomes in the management of anticholinergic refractory overactive bladder.World journal of urology · 2018Observational
- CUA guideline on adult overactive bladder.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2017Article
- A comparative study of electroacupuncture at Zhongliao (BL33) and other acupoints for overactive bladder symptoms.Frontiers of medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo verify whether the combination of transcutaneous electrical neural stimulation (TENS) with oxybutynin in the treatment of women with overactive bladder (OAB) would be more effective than isolated treatments.
methodsWe randomized 75 women with OAB, in three groups: GI--30 min TENS, twice a week; GII--daily slow release 10 mg oxybutynin; and GIII--TENS + oxybutynin (multimodal); all for 12 weeks. Patients were evaluated with validated questionnaires International Consultation on Incontinence-Short Form (ICIQ-SF), International Consultation on Incontinence-OAB (ICIQ-OAB), Symptom bother, and 3-day Voiding diary at weeks 0, 12, and 24.
resultsThe groups were similar before treatment. After treatment, all groups significantly improved in OAB symptoms and quality of life (QoL). At week 12, ICIQ-OAB scores were 5.9, 4.6, and 2.9, in groups I, II, and III, respectively, p = 0.01. At week 24, GI and GIII kept the scores of the end of treatment (week 12), while GII increased ICIQ-OAB from 4.6 to 9.2, p = 0.0001, ICIQ-SF from 9.8 to 13.3, p = 0.0006, and Symptom bother score from 3.4 to 7.0, p = 0.0001.
conclusionsThe multimodal treatment was more effective and TENS alone or in association presented longer lasting results for improvement of clinical symptoms of OAB and QoL.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.