ArticleEuropean radiology2013
Diffusion-weighted magnetic resonance imaging: new perspectives in the diagnostic pathway of non-complicated acute pyelonephritis.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03959163 (The Validity of the Quick Renal MRI in Pediatric Kidney Disease), which is not on this map. Cited by 15 papers.
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The Validity of the Quick Renal MRI in Pediatric Kidney Disease
Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- Imaging evaluation of acute abdominal pain in the pregnant patient.Abdominal radiology (New York) · 2026Review
- Added value of restricted diffusion in acute pyelonephritis: Two cases with different clinical presentations.Radiology case reports · 2026Article
- Glomerulonephritis through the lens of ultrasound and radiology.World journal of nephrology · 2026Review
- MR Imaging of the Upper Urinary Tract: Techniques, Diagnostic Performance, and Imaging Biomarkers.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Review
- The Usefulness and Limitations of Radiologic Findings for Diagnosis of Infectious Diseases: A Call for Antimicrobial Stewardship.Infection & chemotherapy · 2025Review
- Role of MRI in the evaluation of acute pyelonephritis in a high-risk population with renal dysfunction: a prospective study.Emergency radiology · 2023Article
- Diffusion tensor imaging based multiparametric characterization of renal lesions in infants with urinary tract infections: an explorative study.BMC pediatrics · 2021Article
- [Imaging in the acute abdomen-part 2 : Case examples of frequent organ-specific causes: gastrointestinal tract and urogenital system].Der Radiologe · 2021Article
- CT and MRI in Urinary Tract Infections: A Spectrum of Different Imaging Findings.Medicina (Kaunas, Lithuania) · 2021Review
- Relationship of renal apparent diffusion coefficient and functional MR urography in children with pelvicalyceal dilation.Pediatric radiology · 2019Article
- Radiation overexposure from repeated CT scans in young adults with acute abdominal pain.Emergency radiology · 2018Article
- Ureteral dilatation detected in magnetic resonance imaging predicts vesicoureteral reflux in children with urinary tract infection.PloS one · 2018Article
- Core curriculum illustration: acute pyelonephritis.Emergency radiology · 2017Article
- Analysis of non-traumatic truncal back pain in patients who visited an emergency room.Acute medicine & surgery · 2014Article
- Diabetic Kidney Disease: A Syndrome Rather Than a Single Disease.The review of diabetic studies : RDSReview
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe diagnosis of acute pyelonephritis (APN) requires demonstration of parenchymal involvement. When no predisposing conditions are found, non-complicated APN is suspected and CT or MRI should be performed. Diffusion-weighted (DW) MRI might be useful, quicker and cheaper than the standard gadolinium-enhanced (GE) MRI. The aim of this study is to compare DW-MRI with GE-MRI to test its diagnostic accuracy in APN.
methodsOf 318 consecutive patients hospitalised for APN, 279 underwent MRI. Four hundred and fourteen MR studies (first test and follow-up examinations) were gathered and data were processed using Diffusion Analysis software. DW-MRI has been compared with GE-MRI for evaluating diagnostic agreement.
resultsTwo hundred and forty-four patients were diagnosed as having APN; 35 were negative. One hundred and sixty-three APN cases were considered non-complicated and selected for the study. Among the 414 MR examinations, comparing DW-MRI with GE-MRI, positive correlation was found in 258 cases, negative in 133. There were 14 false-negatives and 9 false-positives. DW-MRI achieved sensitivity 95.2 %, specificity 94.9 %, positive predictive value 96.9 %, negative predictive value 92.3 % and accuracy 94.6 %.
conclusionsDW-MRI is reliable for diagnosing non-complicated APN. The high diagnostic agreement between DW-MRI and GE-MRI offers new perspectives in diagnostic management, enabling diagnosis of non-complicated APN without using ionising radiation or contrast media. KEY POINTS: • The diagnosis of acute pyelonephritis (APN) requires demonstration of renal involvement. • Hitherto magnetic resonance imaging required gadolinium enhancement (GE-MRI) to establish this diagnosis. • But diagnostic agreement between diffusion-weighted and GE-MRI offers new diagnostic opportunities. • Quantification of ADC values can help diagnose and monitor APN. • DW-MRI avoids ionising radiation and paramagnetic contrast medium administration.
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