Evidence map›Paper›PMID 23749191›Full record

ArticleNature genetics2013

The duck genome and transcriptome provide insight into an avian influenza virus reservoir species.

Yinhua Huang, Yingrui Li, David W Burt, Hualan Chen, Yong Zhang, Wubin Qian, Heebal Kim, Shangquan Gan, Yiqiang Zhao, Jianwen Li and 41 more

Open access · hybridAbstract read
In one paragraph

Article in Nature genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 455 citations in OpenAlex.

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  14. Antiviral Effects of Avian Interferon-Stimulated Genes.Animals : an open access journal from MDPI · 2024
    Review
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127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

51 authors at 17 institutions in 10 countries.

Yinhua Huang *State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Yingrui Li *BGI-Shenzhen, Shenzhen, China.
David W Burt *The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Hualan ChenNational Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Harbin, China.
Yong ZhangBGI-Shenzhen, Shenzhen, China.
Wubin QianBGI-Shenzhen, Shenzhen, China.
Heebal KimDepartment of Agricultural Biotechnology, Seoul National University, Seoul, Korea.
Shangquan GanState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Yiqiang ZhaoState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Jianwen LiBGI-Shenzhen, Shenzhen, China.
Kang YiBGI-Shenzhen, Shenzhen, China.
Huapeng FengNational Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Harbin, China.
Pengyang ZhuNational Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Harbin, China.
Bo LiBGI-Shenzhen, Shenzhen, China.
Qiuyue LiuState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Suan FairleyWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Katharine E MagorDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
Zhenlin DuState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Xiaoxiang HuState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Laurie GoodmanBGI-Shenzhen, Shenzhen, China.
Hakim TaferDepartment of Computer Science, University of Leipzig, Leipzig, Germany.
Alain VignalLaboratoire de Génétique Cellulaire, Institut National de la Recherche Agronomique (INRA), Castanet-Tolosan, France.
Taeheon LeeDepartment of Agricultural Biotechnology, Seoul National University, Seoul, Korea.
Kyu-Won KimInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Korea.
Zheya ShengState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Yang AnState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Steve SearleWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Javier HerreroEuropean Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Martien A M GroenenAnimal Breeding and Genomics Centre, Wageningen University, Wageningen, The Netherlands.
Richard P M A CrooijmansAnimal Breeding and Genomics Centre, Wageningen University, Wageningen, The Netherlands.
Thomas FarautLaboratoire de Génétique Cellulaire, Institut National de la Recherche Agronomique (INRA), Castanet-Tolosan, France.
Qingle CaiBGI-Shenzhen, Shenzhen, China.
Robert G WebsterDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Jerry R AldridgeDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Wesley C WarrenThe Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA.
Sebastian BartschatDepartment of Computer Science, University of Leipzig, Leipzig, Germany.
Stephanie KehrDepartment of Computer Science, University of Leipzig, Leipzig, Germany.
Manja MarzDepartment of Computer Science, University of Leipzig, Leipzig, Germany.
Peter F StadlerDepartment of Computer Science, University of Leipzig, Leipzig, Germany.
Jacqueline SmithThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Robert H S KrausResource Ecology Group, Wageningen University, Wageningen, The Netherlands.
Yaofeng ZhaoState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Liming RenState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Jing FeiState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Mireille MorissonLaboratoire de Génétique Cellulaire, Institut National de la Recherche Agronomique (INRA), Castanet-Tolosan, France.
Pete KaiserThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Darren K GriffinGenetics School of Biosciences, University of Kent, Kent, UK.
Man RaoState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
Frederique PitelLaboratoire de Génétique Cellulaire, Institut National de la Recherche Agronomique (INRA), Castanet-Tolosan, France.
Jun WangBGI-Shenzhen, Shenzhen, China.
Ning LiState Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China.
China Agricultural University · CNBGI Group (China) · CNLaboratoire de Génétique Cellulaire · FRHarbin Veterinary Research Institute · CNLeipzig University · DESeoul National University · KRUniversity of Edinburgh · GBWageningen University & Research · NLSt. Jude Children's Research Hospital · USUniversity of Vienna · ATWellcome Sanger Institute · GBEuropean Bioinformatics Institute · GBRoslin Institute · GBUniversity of Alberta · CAUniversity of Copenhagen · DKUniversity of Kent · GBWashington University in St. Louis · US

Funding

Biotechnology and Biological Sciences Research Council BBS/E/D/05191130Biotechnology and Biological Sciences Research Council BBS/E/D/20211550Biotechnology and Biological Sciences Research Council BBS/E/D/20211552Biotechnology and Biological Sciences Research Council BBS/E/D/20320000Wellcome Trust 079643Wellcome Trust 095908
6 · The paper itself

Abstract

The duck (Anas platyrhynchos) is one of the principal natural hosts of influenza A viruses. We present the duck genome sequence and perform deep transcriptome analyses to investigate immune-related genes. Our data indicate that the duck possesses a contractive immune gene repertoire, as in chicken and zebra finch, and this repertoire has been shaped through lineage-specific duplications. We identify genes that are responsive to influenza A viruses using the lung transcriptomes of control ducks and ones that were infected with either a highly pathogenic (A/duck/Hubei/49/05) or a weakly pathogenic (A/goose/Hubei/65/05) H5N1 virus. Further, we show how the duck's defense mechanisms against influenza infection have been optimized through the diversification of its β-defensin and butyrophilin-like repertoires. These analyses, in combination with the genomic and transcriptomic data, provide a resource for characterizing the interaction between host and influenza viruses.

Indexed as

Disease ReservoirsGenomeAnimalsBase SequenceChickensDisease VectorsDucksFemaleGeeseHost-Pathogen InteractionsImmunityInfluenza in BirdsMolecular Sequence DataPhylogenySpecies SpecificityTranscriptome

Identifiers

PMID23749191
PMCPMC4003391
OpenAlexW2122016967

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.