ArticleParasitology research2013
Gut transcriptome of replete adult female cattle ticks, Rhipicephalus (Boophilus) microplus, feeding upon a Babesia bovis-infected bovine host.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 48 citations in OpenAlex.
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- Infection with Babesia bovis alters metabolic rates of Rhipicephalus microplus ticks across life stages.Parasites & vectors · 2025Article
- Transcriptomic analysis of Rhipicephalus microplus hemocytes from female ticks infected with Babesia bovis or Babesia bigemina.Parasites & vectors · 2025Article
- Developmental Proteomics Reveals the Dynamic Expression Profile of Global Proteins ofLife (Basel, Switzerland) · 2025Article
- The proteomic content of Varroa destructor gut varies according to the developmental stage of its host.PLoS pathogens · 2024Article
- More than Three Decades of Bm86: What We Know and Where to Go.Pathogens (Basel, Switzerland) · 2023Review
- Transcriptome Profiling ofBiomedicines · 2023Article
- Mapping structural variations iniScience · 2023Article
- Early Transcriptional Changes in the Midgut ofMicroorganisms · 2022Article
- A physiologic overview of the organ-specific transcriptome of the cattle tick Rhipicephalus microplus.Scientific reports · 2020Article
- A transcriptome and proteome of the tick Rhipicephalus microplus shaped by the genetic composition of its hosts and developmental stage.Scientific reports · 2020Article
- Gene expression during the early stages of host perception and attachment in adult female Rhipicephalus microplus ticks.Experimental & applied acarology · 2019Article
- Investigation into limiting dilution and tick transmissibility phenotypes associated with attenuation of the S24 vaccine strain.Parasites & vectors · 2019Article
- The multiple roles of peroxiredoxins in tick blood feeding.Experimental & applied acarology · 2018Review
- A proteomic insight into the midgut proteome of Ornithodoros moubata females reveals novel information on blood digestion in argasid ticks.Parasites & vectors · 2017Article
- DecipheringFrontiers in cellular and infection microbiology · 2017Review
- Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick-Host Interactions.Trends in parasitology · 2016Review
- Midgut proteome of an argasid tick, Ornithodoros erraticus: a comparison between unfed and engorged females.Parasites & vectors · 2015Article
- Constructing and detecting a cDNA library for mites.Parasitology research · 2015Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As it feeds upon cattle, Rhipicephalus (Boophilus) microplus is capable of transmitting a number of pathogenic organisms, including the apicomplexan hemoparasite Babesia bovis, a causative agent of bovine babesiosis. The R. microplus female gut transcriptome was studied for two cohorts: adult females feeding on a bovine host infected with B. bovis and adult females feeding on an uninfected bovine. RNA was purified and used to generate a subtracted cDNA library from B. bovis-infected female gut, and 4,077 expressed sequence tags (ESTs) were sequenced. Gene expression was also measured by a microarray designed from the publicly available R. microplus gene index: BmiGI Version 2. We compared gene expression in the tick gut from females feeding upon an uninfected bovine to gene expression in tick gut from females feeding upon a splenectomized bovine infected with B. bovis. Thirty-three ESTs represented on the microarray were expressed at a higher level in female gut samples from the ticks feeding upon a B. bovis-infected calf compared to expression levels in female gut samples from ticks feeding on an uninfected calf. Forty-three transcripts were expressed at a lower level in the ticks feeding upon B. bovis-infected female guts compared with expression in female gut samples from ticks feeding on the uninfected calf. These array data were used as initial characterization of gene expression associated with the infection of R. microplus by B. bovis.
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