ArticleResearch in developmental disabilities2013
Psychopharmacological treatment in children and adolescents with autism spectrum disorders in Germany.
Article in Research in developmental disabilities, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Pharmacological intervention for irritability, aggression, and self-injury in autism spectrum disorder (ASD).The Cochrane database of systematic reviews · 2023Pooled it
- High-Dose Propranolol for Severe and Chronic Aggression in Autism Spectrum Disorder: A Pilot, Double-Blind, Placebo-Controlled, Randomized Crossover Study.Journal of clinical psychopharmacologyTrial
- Dataset of pharmacotherapy in autism spectrum disorder.Data in brief · 2025Article
- Profile of autism spectrum disorders in Morocco: cross-sectional retrospective study of parents of children with autism.Medicine and pharmacy reports · 2023Article
- Review
- Randomised controlled trials of mood stabilisers for people with autism spectrum disorder: systematic review and meta-analysis.BJPsych open · 2022Review
- Randomised controlled trials of antidepressant and anti-anxiety medications for people with autism spectrum disorder: systematic review and meta-analysis.BJPsych open · 2021Review
- Practitioner's review: medication for children and adolescents with autism spectrum disorder (ASD) and comorbid conditions.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2021Review
- First-Time Users of ADHD Medication Among Children and Adolescents in Germany: An Evaluation of Adherence to Prescribing Guidelines Based on Claims Data.Frontiers in psychiatry · 2021Article
- Do autistic patients change healthcare services utilisation through the transition age? An Italian longitudinal retrospective study.BMJ open · 2019Article
- Prescriptions for Alpha Agonists and Antipsychotics in Children and Youth with Tic Disorders: A Pharmacoepidemiologic Study.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019Article
- Use of Psychotropic Drugs among Children and Adolescents with Autism Spectrum Disorders in Denmark: A Nationwide Drug Utilization Study.Journal of clinical medicine · 2018Article
- Prescription Trends of Psychotropics in Children and Adolescents with Autism Based on Nationwide Health Insurance Data.Journal of Korean medical science · 2017Article
- Clinical predictors of antipsychotic use in children and adolescents with autism spectrum disorders: a historical open cohort study using electronic health records.European child & adolescent psychiatry · 2016Article
- Child and adolescent psychiatry: which knowledge and skills do primary care physicians need to have? A survey in general practitioners and paediatricians.European child & adolescent psychiatry · 2016Article
- Can Bayesian Theories of Autism Spectrum Disorder Help Improve Clinical Practice?Frontiers in psychiatry · 2016Article
- Authors' response to Bachmann and Hoffman's comments on psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study.Psychopharmacology · 2015Article
- Trends in psychopharmacologic treatment of tic disorders in children and adolescents in Germany.European child & adolescent psychiatry · 2015Article
- Determination of psychotropic use in children and adolescents from a prescription database: methodological issues.Psychopharmacology · 2014Article
- Antipsychotic prescription in children and adolescents: an analysis of data from a German statutory health insurance company from 2005 to 2012.Deutsches Arzteblatt international · 2014Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data on psychopharmacological treatment of individuals with autism spectrum disorder (ASD) are scarce, especially for European countries. This study evaluated psychopharmacotherapy utilisation in children and adolescents with a diagnosis of ASD in Germany. Data of a large statutory health insurance company were analysed and outpatients aged 0-24 years with a diagnosis of ASD during a 1-year-period (2009) were identified. For this cohort, the prescription of psychopharmacotherapy was evaluated. Aditionally, we analysed time trends in prescriptions from 2004 to 2009. One thousand one hundred twenty-four patients (75.4% male; mean age: 11.1 years) matched the inclusion criteria. The prevalence of ASD was 0.37% in males and 0.12% in females, respectively. Of all ASD patients, 33.0% were prescribed psychotropic drugs in 2009. 12.5% of ASD patients were treated with stimulants or atomoxetine, 11.7% with antipsychotics, 9.1% with antiepileptics, 6.8% with benzodiazepines, and 3.8% with antidepressants/SSRI. Regarding substances, methylphenidate (24.4% of all psychotropic prescriptions), risperidone (13.3%) and valproate (9.1%) were most frequently prescribed. Psychopharmacologic treatment prevalence was age-related and increased from 16.3% in individuals aged 0-4 years to 55.1% in 20-24 year olds. From 2004 to 2009, the proportion of ASD patients treated with psychotropic drugs rose from 25.9% to 33.0%. This naturalistic study furnishes evidence that the proportion of ASD patients treated with psychotropic drugs has grown considerably in Germany over the least years, with methylphenidate and risperidone being the most frequently prescribed substances. Compared with data from the USA, the proportion of ASD patients with psychopharmacological treatment is noticeably lower in Germany.
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