Evidence map›Paper›PMID 23747242›Full record

ArticleCell metabolism2013

Novel regulator of enterohepatic bile acid signaling protects against hypercholesterolemia.

Paul A Dawson

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell metabolism, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Paul A DawsonDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Electronic address: pdawson@wakehealth.edu.
Wake Forest University · US

Funding

ILEAL BILE ACID TRANSPORTER METABOLISM AND REGULATIONR01DK047987 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DAWSON, PAUL A · 2000 to 2021
$6.8M
NIDDK NIH HHS R01 DK047987
6 · The paper itself

Abstract

Hypercholesterolemia is a major cause of cardiovascular disease and can be treated by targeting bile acid and cholesterol metabolism. Vergnes et al. (2013) now identify Diet1 as a novel regulator of fibroblast growth factor 15/19 production and bile acid biosynthesis.

Indexed as

Lipid MetabolismAnimalsBile Acids and SaltsCarrier ProteinsCholesterol 7-alpha-HydroxylaseFibroblast Growth FactorsHumansBile Acids and SaltsCarrier ProteinsCholesterol 7-alpha-HydroxylaseCyp7a1 protein, mouseDiet1 protein, mousefibroblast growth factor 15, mouseFibroblast Growth Factors

Identifiers

PMID23747242
PMCPMC3805117
OpenAlexW1972024147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.