Evidence map›Paper›PMID 23747082›Full record

ArticleLeukemia research2013

Geriatric assessment in older patients with acute myeloid leukemia: a retrospective study of associated treatment and outcomes.

Alexander E Sherman, Gabriela Motyckova, K Rebecca Fega, Daniel J Deangelo, Gregory A Abel, David Steensma, Martha Wadleigh, Richard M Stone, Jane A Driver

Abstract read
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In one paragraph

Article in Leukemia research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Peripheral blood CD3British journal of haematology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander E ShermanCollege of Medicine, University of Cincinnati, Cincinnati, OH, United States.
Gabriela Motyckova
K Rebecca Fega
Daniel J Deangelo
Gregory A Abel
David Steensma
Martha Wadleigh
Richard M Stone
Jane A Driver

Funding

Greater Boston Medical Student Training in Aging ResearchT35AG038027 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI DRIVER, JANE A, MCLAUGHLIN-GAVIN, CARA · 2010 to 2024
$991k
NIA NIH HHS T35 AG038027
6 · The paper itself

Abstract

We explored whether geriatric assessment variables predicted mortality in addition to known prognostic factors in 101 patients aged ≥ 65 with newly diagnosed AML. Baseline comorbidity score (HR=1.92; 95%CI 1.18-3.11), difficulty with strenuous activity (HR=2.18; 95%CI 1.19-4.00), and pain (HR=2.17; 95%CI 1.19-3.97) were independent prognostic factors for greater risk of death in a multivariable model that included cytogenetic risk group. They remained independent predictors in the subset of patients with baseline ECOG PS 0-1. Our results support the use of geriatric assessment to better predict prognosis in older patients with AML, even among those with excellent functional status.

Indexed as

Geriatric AssessmentQuality of LifeAgedAged, 80 and overComorbidityFemaleFollow-Up StudiesHumansLeukemia, Myeloid, AcuteMalePrognosisProspective StudiesRetrospective StudiesSurvival RateAcuteComorbidityGeriatric assessmentLeukemiaMyeloidPerformance statusPrognosis

Identifiers

PMID23747082
PMCPMC3735611

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.