ArticleSchizophrenia research2013
Demographic, socio-environmental, and substance-related predictors of duration of untreated psychosis (DUP).
Article in Schizophrenia research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 73 citations in OpenAlex.
- Relationship Between Serum NMDA Receptor Antibodies and Response to Antipsychotic Treatment in First-Episode Psychosis.Biological psychiatry · 2021Trial
- "I Know What I Need": A Mixed Methods Study of Mental Health-Seeking Behaviors in Formerly Incarcerated Black Men.Journal of racial and ethnic health disparities · 2025Article
- Associations between rural/urban status, duration of untreated psychosis and mode of onset of psychosis: a mental health electronic clinical records analysis in the East of England, UK.Social psychiatry and psychiatric epidemiology · 2025Article
- Changes in knowledge, behavioural expectations, self-efficacy, and stigma after an educational campaign about early psychosis for jail correction officers.Early intervention in psychiatry · 2023Article
- Systematic review of pathways to care in the U.S. for Black individuals with early psychosis.NPJ schizophrenia · 2021Review
- Duration of Untreated Disorder and Cannabis Use: An Observational Study on a Cohort of Young Italian Patients Experiencing Psychotic Experiences and Dissociative Symptoms.International journal of environmental research and public health · 2021Observational
- Similarities and Differences in Associations Between Duration of Untreated Psychosis (DUP) and Demographic, Premorbid, and Symptom Severity Measures in Two Samples of First-Episode Psychosis Patients from Mexico and the United States.The Psychiatric quarterly · 2020Article
- Neighborhood-level predictors of age at onset and duration of untreated psychosis in first-episode psychotic disorders.Schizophrenia research · 2020Article
- Article
- Longer Duration of Untreated Psychosis Hinders Improvement in Treatment of Chronic Schizophrenia: Community Based Early Intervention is an Evidence Based Option.Community mental health journal · 2017Article
- Canadian Guidelines for the Pharmacological Treatment of Schizophrenia Spectrum and Other Psychotic Disorders in Children and Youth.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2017Review
- Marijuana use in the immediate 5-year premorbid period is associated with increased risk of onset of schizophrenia and related psychotic disorders.Schizophrenia research · 2016Article
- Cannabis and Psychosis: a Critical Overview of the Relationship.Current psychiatry reports · 2016Review
- Social and spatial heterogeneity in psychosis proneness in a multilevel case-prodrome-control study.Acta psychiatrica Scandinavica · 2015Article
- Substance use and duration of untreated psychosis in KwaZulu-Natal, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South AfricaArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveLonger duration of untreated psychosis (DUP) is associated with poorer early-course and long-term outcomes, and is a target of early detection and intervention efforts. Given the paucity of research on childhood and adolescent stressors (e.g., maltreatment and neighborhood disorder) as potential predictors of DUP, limited research on premorbid substance use as a determinant of DUP, and inconclusive findings on the association between DUP and neurocognition, we conducted three sets of analyses to address these issues. Mode of onset of psychosis was also considered, given its established role as an illness-level correlate of DUP.
methodsWe rigorously assessed DUP and other pertinent variables in 180 predominantly African American, low-income, and socially disadvantaged first-episode psychosis patients hospitalized in five psychiatric units.
resultsMode of onset of psychosis, prior incarceration, and the level of childhood/adolescent maltreatment were all significant independent predictors of DUP. Regarding premorbid substance use, having ever used cannabis and the amount of premorbid alcohol use were significantly associated with DUP. None of the seven neurocognitive domains assessed were even modestly, or clinically meaningfully, associated with DUP.
conclusionsThese and other findings on DUP may be informative for early detection and intervention services. For example, such services might benefit from special outreach to criminal justice settings and disadvantaged neighborhoods, and to young people likely to have a history of childhood/adolescent maltreatment and gradually developing psychotic symptoms.
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