ReviewJournal of neuroendocrinology2013
Recent evidence for rapid synthesis and action of oestrogens during auditory processing in a songbird.
Review in Journal of neuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Estrogen profiling in blood and brain: Effects of season and an aggressive interaction in a songbird.PloS one · 2025Article
- Spatial and temporal specificity of neuroestradiol provision in the songbird.Journal of neuroendocrinology · 2023Review
- A brain for all seasons: An in vivo MRI perspective on songbirds.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2022Review
- Aromatase and nonaromatase neurons in the zebra finch secondary auditory forebrain are indistinct in their song-driven gene induction and intrinsic electrophysiological properties.The European journal of neuroscience · 2021Article
- Testosterone synthesis in the female songbird brain.Hormones and behavior · 2020Article
- Auditory learning in an operant task with social reinforcement is dependent on neuroestrogen synthesis in the male songbird auditory cortex.Hormones and behavior · 2020Article
- Acute neuroestrogen blockade attenuates song-induced immediate early gene expression in auditory regions of male and female zebra finches.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Article
- Steroid profiles in quail brain and serum: Sex and regional differences and effects of castration with steroid replacement.Journal of neuroendocrinology · 2019Article
- Neuroestrogens rapidly shape auditory circuits to support communication learning and perception: Evidence from songbirds.Hormones and behavior · 2018Review
- A Membrane G-Protein-Coupled Estrogen Receptor Is Necessary but Not Sufficient for Sex Differences in Zebra Finch Auditory Coding.Endocrinology · 2018Article
- The Value of Comparative Animal Research: Krogh's Principle Facilitates Scientific Discoveries.Policy insights from the behavioral and brain sciences · 2018Article
- ZENK induction in the zebra finch brain by song: Relationship to hemisphere, rhythm, oestradiol and sex.Journal of neuroendocrinology · 2017Article
- Topography and Lateralized Effect of Acute Aromatase Inhibition on Auditory Processing in a Seasonal Songbird.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Socially induced serotonergic fluctuations in the male auditory midbrain correlate with female behavior during courtship.Journal of neurophysiology · 2016Article
- The importance of neural aromatization in the acquisition, recall, and integration of song and spatial memories in passerines.Hormones and behavior · 2015Review
- Rapid Effects of Estradiol on Aggression in Birds and Mice: The Fast and the Furious.Integrative and comparative biology · 2015Review
- Neurohormones, Brain, and Behavior: A Comparative Approach to Understanding Rapid Neuroendocrine Action.Integrative and comparative biology · 2015Article
- Sex differences and rapid estrogen signaling: A look at songbird audition.Frontiers in neuroendocrinology · 2015Review
- He hears, she hears: are there sex differences in auditory processing?Developmental neurobiology · 2015Article
- Seasonal plasticity of precise spike timing in the avian auditory system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
It is now clear that oestrogens are not only circulating reproductive hormones, but that they also have neurotransmitter-like properties in a wide range of brain circuits. The view of oestrogens as intrinsic neuromodulators that shape behaviour has been bolstered by a series of recent developments from multiple vertebrate model systems. Here, we review several recent findings from studies of songbirds showing how the identified neural circuits that govern auditory processing and sensorimotor integration are modulated by the local and acute production of oestrogens. First, studies using in vivo microdialysis demonstrate that oestrogens fluctuate in the auditory cortex (30-min time bin resolution) when songbirds are hearing song and interacting with conspecifics. Second, oestrogens rapidly boost the auditory-evoked activity of neurones in the same auditory cortical region, enhancing auditory processing. Third, local pharmacological blockade of oestrogen signalling in this region impairs auditory neuronal responsiveness, as well as behavioural song preferences. Fourth, the rapid actions of oestrogens that occur within the auditory cortex can propagate downstream (trans-synaptically) to sensorimotor circuits to enhance the neural representation of song. Lastly, we present new evidence showing that the receptor for the rapid actions of oestradiol is likely in neuronal membranes, and that traditional nuclear oestrogen receptor agonists do not mimic these rapid actions. Broadly speaking, many of these findings are observed in both males and females, emphasising the fundamental importance of oestrogens in neural circuit function. Together, these and other emergent studies provide support for rapid, brain-derived oestrogen signalling in regulating sensorimotor integration, learning and perception.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.