ReviewJournal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 532013
Future directions in the study of social relationships as regulators of the HPA axis across development.
Review in Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it, 152 citations in OpenAlex.
- Psychophysiology of Parenting School-Aged Children: A Systematic Review of the Physiological Correlates of Parenting Behaviors.Developmental psychobiology · 2025Pooled it
- Early Exposure to a Parent's Alcohol Use Disorder as an Adverse Childhood Experience: Neurobiological and Clinical Consequences in Adulthood.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- Early Childhood Emotional, Relational, and Stress-Related Outcomes Following Infant Cardiac Surgery.Developmental psychobiology · 2026Article
- Connection after correction: Parent-child relationships following early cardiac surgery.Infant mental health journal · 2026Article
- Social withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability.Schizophrenia research · 2026Article
- AI outperforms humans in establishing interpersonal closeness in emotionally engaging interactions, but only when labelled as human.Communications psychology · 2026Article
- Mother infant cortisol levels and maternal childhood adversity.Scientific reports · 2025Article
- Early predictors of late childhood behavioural outcomes following very preterm birth.Psychological medicine · 2025Article
- Maternal Childhood Trauma and Offspring Hypothalamic-Pituitary-Adrenal Axis Function from Infancy to 6 Years of Age.Developmental psychobiology · 2025Article
- Childhood adversity and time to pregnancy in a preconception cohort.American journal of epidemiology · 2024Article
- Stress and substance use disorders: risk, relapse, and treatment outcomes.The Journal of clinical investigation · 2024Review
- Does extreme psychological burden (Hamas terrorist attack on October 7th, 2023) affect in vitro fertilization outcome?Journal of assisted reproduction and genetics · 2024Article
- Associations of prenatal and childhood Pb exposure with allostatic load in adolescence: Findings from the ELEMENT cohort study.Environmental research · 2023Article
- Amygdala circuit transitions supporting developmentally-appropriate social behavior.Neurobiology of learning and memory · 2023Review
- Attachment to Mother and Father, Sleep, and Well-Being in Late Middle Childhood.International journal of environmental research and public health · 2023Article
- The interplay of family history of depression and early trauma: associations with lifetime and current depression in the German national cohort (NAKO).Frontiers in epidemiology · 2023Article
- Effects of physical activity in child and adolescent depression and anxiety: role of inflammatory cytokines and stress-related peptide hormones.Frontiers in neuroscience · 2023Review
- Stimulated Parotid Saliva Is a Better Method for Depression Prediction.Biomedicines · 2022Article
- Pain-related stigma as a social determinant of health in diverse pediatric pain populations.Frontiers in pain research (Lausanne, Switzerland) · 2022Review
- Early Adolescents' Experiences During the COVID-19 Pandemic and Changes in Their Well-Being.Frontiers in public health · 2022Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Many promising findings support the notion that social relationships can dampen hypothalamic-pituitary-adrenocortical (HPA) axis stress responses and protect individuals from maladaptive psychological and physical disease states. Despite the public health relevance of this topic, little is known about developmental changes in the social regulation of the HPA system, with most prior research having focused on early childhood and adulthood. This gap is particularly striking with regards to adolescence, an age period when it seems likely that reliance on parents as sources of stress-buffering decreases, even as the security of friends and relationship partners as stress buffers may not yet be certain. Furthermore, we speculate that early life stress or abnormal social experiences may impact the propensity to draw mental and physical health benefits from social relationships, but more empirical support for these ideas is needed. Last, research linking social support to cumulative life stress has mostly relied on self-report measures of stress, making it difficult to show that social support impacts the type of chronic stress exposure that is associated with increased allostatic load or "wear and tear" on the body and on psychological functioning. Recent advancements in methodology (e.g., assessing hair cortisol levels) as well as composite measures of allostatic load using biomarkers that capture the activity of multiple neuroendocrine, cardiovascular, immune, and metabolic systems will allow us to ask new questions about the extent to which social relationships can impact cumulative life stress and health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.