SynthesisThe Cochrane database of systematic reviews2013
Interventions for the restorative care of amelogenesis imperfecta in children and adolescents.
Synthesis in The Cochrane database of systematic reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 58 citations in OpenAlex.
- Seeking perspectives of a dedicated paediatric dental Anomalies Clinic: a retrospective evaluation and satisfaction survey.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Minimally Invasive Transitional Full-Mouth Adhesive Rehabilitation of a Patient With Amelogenesis Imperfecta Using Direct and Indirect Composite Restorations: A Case Report.Case reports in dentistry · 2026Article
- Functional and Aesthetic Treatment of Patients With Tooth Structure Anomalies: A Narrative Review.Cureus · 2025Review
- The circadian clock in enamel development.International journal of oral science · 2024Review
- Establishment of a clinical network for children with amelogenesis imperfecta and dentinogenesis imperfecta in the UK: 4-year experience.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Article
- Impact of claudin-10 deficiency on amelogenesis: Lesson from a HELIX tooth.Annals of the New York Academy of Sciences · 2022Article
- The burden of dental care in Amelogenesis Imperfecta paediatric patients in the UK NHS: a retrospective, multi-centred analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Article
- Dental management of tricho-dento-osseous syndrome in adolescent patients: Literature review and case presentation.Dental research journal · 2021Article
- Retrospective study of patients with amelogenesis imperfecta treated with different bonded restoration techniques.Clinical and experimental dental research · 2020Article
- Canine models of human amelogenesis imperfecta: identification of novel recessive ENAM and ACP4 variants.Human genetics · 2019Article
- Genetic testing for amelogenesis imperfecta: knowledge and attitudes of paediatric dentists.British dental journal · 2018Article
- Amelogenesis Imperfecta; Genes, Proteins, and Pathways.Frontiers in physiology · 2017Review
- Review
- Aesthetic and functional rehabilitation of the primary dentition affected by amelogenesis imperfecta.Case reports in dentistry · 2015Article
- A systematic map of systematic reviews in pediatric dentistry--what do we really know?PloS one · 2015Article
- Methodological quality and implications for practice of systematic Cochrane reviews in pediatric oral health: a critical assessment.BMC oral health · 2014Review
Corrections and comments
- Commented on by
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAmelogenesis imperfecta (AI) is a tooth development disorder in which the teeth are covered with thin, abnormally formed enamel. This enamel is easily fractured and damaged, which affects the appearance of the teeth, especially if left untreated. Negative psychological outcomes, due to compromised appearance and function, in patients with AI, have been found to compromise a person's attractiveness and reduce social interaction. The treatment used depends on the severity of the problem.
objectivesTo compare the success rates of different restorative materials and techniques used for the restoration of anterior and posterior teeth with AI in terms of patient satisfaction (aesthetics and sensitivity) and function. SEARCH
methodsWe searched the Cochrane Oral Health Group's Trials Register (to 18 April 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2013, Issue 3), MEDLINE via OVID (1946 to 18 April 2013), EMBASE via OVID (1980 to 18 April 2013), CINAHL via EBSCO (1980 to 18 April 2013), Abstracts of the Conference Proceedings of the International Association for Dental Research (2001 to 18 April 2013) and reference lists of relevant articles. There were no restrictions on language or date of publication in the electronic searches. SELECTION CRITERIA: Randomised controlled trials where children and adolescents with AI who required restoration of teeth were allocated to different restoration techniques would have been selected. Outcomes which would have been evaluated were patient satisfaction, aesthetics, masticatory function and longevity of restorations. DATA COLLECTION AND ANALYSIS: Two review authors would have extracted data and assessed the risk of bias in included studies independently. Disagreement between the two authors would have been resolved by consulting a third review author. First authors were contacted for additional information and unpublished data. MAIN
resultsNo studies met the inclusion criteria for this review. AUTHORS'
conclusionsWe found no randomised controlled trials of restorative treatments for children and adolescents with AI, and therefore there is no evidence as to which is the best restoration. Well defined randomised controlled trials which recruit children and adolescents and focus on the type and severity of the disorder should be undertaken to determine the best intervention for restoring teeth affected by AI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.