ArticleJournal of affective disorders2013
Clinical phenotype of bipolar disorder with comorbid binge eating disorder.
Article in Journal of affective disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Comorbidity of binge eating disorder and other psychiatric disorders: a systematic review.BMC psychiatry · 2024Pooled it
- A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder.The Australian and New Zealand journal of psychiatry · 2015Pooled it
- Binge Eating Disorder in Bipolar I Disorder: Prevalence, Childhood Trauma, and Clinical Correlates.Noro psikiyatri arsivi · 2026Article
- A Cross-Sectional Analysis of Social Determinants of Health in Bipolar Disorder: Exploring Gender-Related Differences.Bipolar disorders · 2025Article
- Prevalence and Correlates of Eating Disorder Symptoms in Adolescents with Bipolar I Disorder.Journal of child and adolescent psychopharmacology · 2024Article
- Prediction of medical admissions after psychiatric inpatient hospitalization in bipolar disorder: a retrospective cohort study.Frontiers in psychiatry · 2024Article
- Prevalence of eating disorders in patients with bipolar disorder: a scoping review of the literature.Consortium psychiatricum · 2023Article
- The Mediating Role of Time Perspective in the Relationship between Chronotype and Suicide in Bipolar Disorder.Behavioral sciences (Basel, Switzerland) · 2022Article
- The genetics of bipolar disorder with obesity and type 2 diabetes.Journal of affective disorders · 2022Review
- TCF7L2 lncRNA: a link between bipolar disorder and body mass index through glucocorticoid signaling.Molecular psychiatry · 2021Article
- Prevalence of Binge-Eating Disorder and Its Association with Nicotine Dependence Among Under-Graduate Students at a Saudi Public University.Journal of multidisciplinary healthcare · 2021Article
- Topiramate precipitating a manic episode in a bipolar patient comorbid with binge eating disorder: A case report.Medicine · 2019Article
- Eating disorders, bipolar disorders and other mood disorders: complex and under-researched relationships.Journal of eating disorders · 2019Article
- Prevalence and Associated Features of Anxiety Disorder Comorbidity in Bipolar Disorder: A Meta-Analysis and Meta-Regression Study.Frontiers in psychiatry · 2018Article
- Lifetime eating disorder comorbidity associated with delayed depressive recovery in bipolar disorder.International journal of bipolar disorders · 2017Article
- DifferentialFrontiers in cellular neuroscience · 2017Article
- Obesity, but not metabolic syndrome, negatively affects outcome in bipolar disorder.Acta psychiatrica Scandinavica · 2016Article
- A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.Journal of affective disorders · 2016Article
- National survey and community advisory board development for a bipolar disorder biobank.Bipolar disorders · 2015Article
- Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.Molecular psychiatry · 2014Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 3 countries.
Funding
Abstract
backgroundTo explore the relationship between binge eating disorder (BED) and obesity in patients with bipolar disorder (BP).
methods717 patients participating in the Mayo Clinic Bipolar Biobank completed structured diagnostic interviews and questionnaires for demographic and illness-related variables. They also had weight and height measured to determine body mass index (BMI). The effects of BED and obesity (BMI≥30 kg/m(2)), as well as their interaction, were assessed on one measure of general medical burden and six proxies of psychiatric illness burden.
results9.5% of patients received a clinical diagnosis of BED and 42.8% were obese. BED was associated with a significantly elevated BMI. Both BED and obesity were associated with greater psychiatric and general illness burden, but illness burden profiles differed. After controlling for obesity, BED was associated with suicidality, psychosis, mood instability, anxiety disorder comorbidity, and substance abuse comorbidity. After controlling for BED status, obesity was associated with greater general medical comorbidity, but lower substance abuse comorbidity. There were no significant interaction effects between obesity and BED, or BMI and BED, on any illness burden outcome. LIMITATIONS: There may have been insufficient power to detect interactions between BED and obesity.
conclusionsAmong patients with BP, BED and obesity are highly prevalent and correlated, but associated with different profiles of enhanced illness burden. As the association of BED with greater psychiatric illness burden remained significant even after accounting for the effect of obesity, BP with BED may represent a clinically important sub-phenotype.
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