ArticleOrganic letters2013
A practical method for the synthesis of highly enantioenriched trans-1,2-amino alcohols.
Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Harnessing Bacillus inaquosorum AGSP2 for enhancing ω-transaminase production through classical and AI-supported statistical design.Scientific reports · 2026Article
- Stereoselective Biosynthesis of Bichiral Amino Alcohols from Diketone via Difunctionalization.ACS omega · 2025Article
- Article
- Rapid Optical Determination of Enantiomeric Excess, Diastereomeric Excess, and Total Concentration Using Dynamic-Covalent Assemblies: A Demonstration Using 2-Aminocyclohexanol and Chemometrics.Journal of the American Chemical Society · 2019Article
- γ-, Diastereo-, and Enantioselective Addition of MEMO-Substituted Allylboron Compounds to Aldimines Catalyzed by Organoboron-Ammonium Complexes.Angewandte Chemie (International ed. in English) · 2018Article
- Catalytic Annulation of Epoxides with Heterocumulenes by the Indium-Tin System.Molecules (Basel, Switzerland) · 2018Article
- Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system.Biotechnology and bioengineering · 2018Article
- A broadly applicable and practical oligomeric (salen) Co catalyst for enantioselective epoxide ring-opening reactions.Tetrahedron · 2014Article
- General approach to the synthesis of the chlorosulfolipids danicalipin A, mytilipin A, and malhamensilipin A in enantioenriched form.The Journal of organic chemistry · 2014Article
- Mechanistic basis for high stereoselectivity and broad substrate scope in the (salen)Co(III)-catalyzed hydrolytic kinetic resolution.Journal of the American Chemical Society · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A highly enantioselective addition of phenyl carbamate to meso-epoxides has been developed to efficiently generate protected trans-1,2-amino alcohols. This transformation is promoted by an oligomeric (salen)Co-OTf catalyst and has been used to prepare two useful 2-aminocycloalkanol hydrochlorides in enantiopure form on a multigram scale from commercially available starting materials.
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Registered trials
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