ArticlePloS one2013
Association of cardiovascular burden with mobility limitation among elderly people: a population-based study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 76 citations in OpenAlex.
- Extending contingency management for smoking cessation to patients with or at risk for cardiovascular disease: A preliminary trial of a home-based intervention.Experimental and clinical psychopharmacology · 2024Trial
- Physical Resilience May Offset Mortality Risks Associated With Genetic Predisposition to Shorter Survival: A Population-based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Development and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults.Journal of the American Heart Association · 2025Article
- Chinese validation of "subjective motoric cognitive risk syndrome" screening tool in patients with coronary artery disease using Rasch analysis.Frontiers in aging · 2025Article
- Life-space mobility and cognitive function: The REasons for geographic and racial differences in stroke (REGARDS) study.Journal of the American Geriatrics Society · 2024Article
- Article
- Hand Grip Strength Relative to Waist Circumference as a Means to Identify Men and Women Possessing Intact Mobility in a Cohort of Older Adults with Type 2 Diabetes.Biomedicines · 2023Article
- Physical and Functional Clinical Profile of Older Adults in Specialized Geriatric Rehabilitation Care Services in Saguenay-Québec: A Retrospective Study at La Baie Hospital.International journal of environmental research and public health · 2022Article
- A Systematic Review and Meta-analysis of Total Ankle Arthroplasty or Ankle Arthrodesis for Treatment of Osteoarthritis in Patients With Diabetes.Foot & ankle orthopaedics · 2022Article
- Mobility Status Plays an Important Role in the Risk of Cardiovascular Rehospitalizations in Patients with Heart Failure Undergoing Cardiac Rehabilitation: A Retrospective Cohort Study.Journal of personalized medicine · 2022Article
- Using multiple imputation and intervention-based scenarios to project the mobility of older adults.BMC geriatrics · 2022Article
- Exploring the Relationship between Frailty, Functional Status, Polypharmacy, and Quality of Life in Elderly and Middle-Aged Patients with Cardiovascular Diseases: A One-Year Follow-Up Study.International journal of environmental research and public health · 2022Article
- Poor Physical Capacity Combined With High Body Fat Percentage as an Independent Risk Factor for Incident Hypertension in Chinese Suburb-Dwelling Older Adults.Frontiers in public health · 2022Article
- Combined effect of obesity and low physical performance on the incidence of hypertension in Chinese community-dwelling older population.Journal of human hypertension · 2021Article
- Imaging-based indices of Neuropathology and gait speed decline in older adults: the atherosclerosis risk in communities study.Brain imaging and behavior · 2021Article
- SART and Individual Trial Mistake Thresholds: Predictive Model for Mobility Decline.Geriatrics (Basel, Switzerland) · 2021Article
- Asymptomatic carotid artery stenosis is associated with cerebral hypoperfusion.Journal of vascular surgery · 2021Article
- Motoric cognitive risk syndrome: Integration of two early harbingers of dementia in older adults.Ageing research reviews · 2020Review
- The relationship between lead and cadmium levels and functional dependence among elderly participants.Environmental science and pollution research international · 2020Article
- Association Between Motor and Cognitive Performances in Elderly With Atrial Fibrillation: Strat-AF Study.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular risk factors (CRFs) such as smoking and diabetes have been associated with mobility limitations among older adults. We seek to examine to what extent individual and aggregated CRFs and cardiovascular diseases (CVDs) are associated with mobility limitation.
methodsThe study sample included 2725 participants (age ≥60 years, mean age 72.7 years, 62% women) in the Swedish National Study on Aging and Care in the Kungsholmen district of central Stockholm, Sweden, who were living either at their own home or in institutions. Data on demographic features, CRFs, and CVDs were collected through interview, clinical examination, self-reported history, laboratory tests, and inpatient register. Mobility limitation was defined as walking speed <0.8 m/s. Data were analyzed using multiple logistic models controlling for potential confounders.
resultsOf the 2725 participants, 581 (21.3%) had mobility limitation. The likelihood of mobility limitation increased linearly with the increasing number of CRFs (i.e., hypertension, high C-reactive protein, obesity, diabetes and smoking) (p for linear trend<0.010) and of CVDs (i.e., ischemic heart disease, atrial fibrillation, heart failure and stroke) (p for linear trend<0.001). There were statistical interactions of aggregated CRFs with age and APOE ε4 allele on mobility limitation (p interaction<0.05), such that the association of mobility limitation with aggregated CRFs was statistically evident only among people aged <80 years and among carriers of the APOE ε4 allele.
conclusionAggregations of multiple CRFs and CVDs are associated with an increased likelihood of mobility limitation among older adults; however the associations of CRFs with mobility limitation vary by age and genetic susceptibility.
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