Evidence map›Paper›PMID 23741245›Full record

ArticleOncology letters2012

EphA2 silencing in nasopharyngeal carcinoma leads to decreased proliferation, invasion and increased sensitization to paclitaxel.

Pingqing Tan, Yong Liu, Changyun Yu, Zhongwu Su, Guo Li, Xiaojuan Zhou, Donghai Huang, Xin Zhang, Yuanzheng Qiu, Yongquan Tian

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. WIP1 regulates the proliferation and invasion of nasopharyngeal carcinoma in vitro.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Pingqing TanDepartment of Otolaryngology, Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008 ; Otolaryngology Major Disease Research Key Laboratory of Hunan Province, Changsha, Hunan 410008.
Yong Liu
Changyun Yu
Zhongwu Su
Guo Li
Xiaojuan Zhou
Donghai Huang
Xin Zhang
Yuanzheng Qiu
Yongquan Tian
Central South University · CNXiangya Hospital Central South University · CNThe First Hospital of Changsha · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EphA2 is frequently overexpressed and functionally altered in a variety of human cancers. However, its roles in human nasopharyngeal carcinoma (NPC) remain unclear. To investigate the roles of EphA2 in the development and progression of NPC, we initially evaluated the expression pattern of EphA2 protein in NPC tissues using western blotting and CCK-8 assay. Fluorescence-activated cell sorting analysis and invasion assay were conducted to observe the effects of EphA2 inhibition

Indexed as

drug resistanceEphA2metastasisnasopharyngeal carcinomapaclitaxel

Identifiers

PMID23741245
PMCPMC3673643
OpenAlexW2022895299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.