Evidence map›Paper›PMID 23741107›Full record

ArticleInternational journal of human genetics2013

Status of

Somiranjan Ghosh, Tomas Trnovec, Lubica Palkovicova, Eric P Hoffman, Kareem Washington, Sisir K Dutta

Abstract read
In one paragraph

Article in International journal of human genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Liver Disease in a Residential Cohort With Elevated Polychlorinated Biphenyl Exposures.Toxicological sciences : an official journal of the Society of Toxicology · 2018
    Article
  5. Article
  6. The spatial distribution of human exposure to PCBs around a former production site in Slovakia.Environmental science and pollution research international · 2015
    Article
  7. Article
  8. Article
  9. Biomarkers linking PCB exposure and obesity.Current pharmaceutical biotechnology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Somiranjan GhoshDepartment of Biology, Howard University, Washington DC, USA.
Tomas Trnovec
Lubica Palkovicova
Eric P Hoffman
Kareem Washington
Sisir K Dutta
Howard University · USSlovak Medical University · SKChildren's National · US

Funding

Early Disease Biomarkers of PCB-exposed Human PopulationU01ES016127 · NIEHS · HOWARD UNIVERSITY · PI DUTTA, SISIR K · 2007 to 2010
$1.7M
NIEHS NIH HHS U01 ES016127
6 · The paper itself

Abstract

Earlier, we have reported that Polychlorinated Biphenyls (PCBs) exposure in Slovak population has made differential gene expression that has linked to the possibilities of some diseases and disorder development in the studied population. Here we report that down-regulation of LEPR (Leptin receptor) gene in the 45-month children may have been following consequences in developing obesity later in life. A pilot high-throughput qRT-PCR [Taqman Low Density Array (TLDA)] study in a small population also corroborated the gene-expression results, and their pathways underlying the consequences of the diseases, amid further detailed large-scale population validation. The study shows the opportunity of predicting long-term effects of chemical exposures using selected genomic classifiers may reflect exposure effect and risk from environmental toxicants.

Indexed as

Gene ExpressionLeptin ReceptorObesityPCBs

Identifiers

PMID23741107
PMCPMC3670706
OpenAlexW1801472566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.