ArticleAnnals of surgical oncology2013
International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers.
Article in Annals of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Surgical Management of Early-Onset Breast Cancer Among Young BRCA1 and BRCA2 Carriers.JAMA network open · 2026Article
- Global Disparities in Insurance Coverage of Post-Mastectomy Breast Reconstruction.Annals of surgical oncology · 2026Review
- Trends in breast reconstruction for BRCA1/2, PALB2 and other high penetrance germline pathogenic variant carriers undergoing risk reducing mastectomy.Familial cancer · 2026Article
- Cumulative Medical Costs of Prepectoral Versus Subpectoral Implant-based Breast Reconstruction: A Single-Center Retrospective Analysis.Plastic and reconstructive surgery. Global open · 2026Article
- Effects of breast size on breast reconstruction in BRCA mutation carriers and genetic high-risk patients after bilateral mastectomy.Breast cancer (Tokyo, Japan) · 2025Article
- Quality of Life after Alloplastic versus Autologous Breast Reconstruction: The Influence of Patient Characteristics on Outcomes.Breast care (Basel, Switzerland) · 2025Article
- Current Trends in Breast Reconstruction following Bilateral Prophylactic Mastectomy.Plastic and reconstructive surgery. Global open · 2022Article
- Analysis of Secondary Surgeries after Immediate Breast Reconstruction for Cancer Compared with Risk Reduction.Plastic and reconstructive surgery. Global open · 2020Article
- Precaution Costs: The Presumption of Breast Cancer Seeding and Its Impact on Surgical Expenditure.Plastic and reconstructive surgery. Global open · 2020Article
- Higher Distress in Patients with Breast Cancer Is Associated with Declining Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2020Article
- Using Bionics to Restore Sensation to Reconstructed Breasts.Frontiers in neurorobotics · 2020Article
- Augmented reality mastectomy surgical planning prototype using the HoloLens template for healthcare technology letters.Healthcare technology letters · 2019Article
- Geisinger MyCodeCase reports in plastic surgery & hand surgery · 2019Article
- Prophylactic Bilateral Nipple-sparing Mastectomy and a Staged Breast Reconstruction Technique: Preliminary Results.Breast cancer : basic and clinical research · 2016Article
Corrections and comments
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Authors and funding
18 authors at 15 institutions in 5 countries.
Funding
Abstract
backgroundBreast reconstruction is an option for women with BRCA1 or BRCA2 mutations who elect to undergo prophylactic mastectomy to prevent breast cancer. We report on the uptake of breast reconstruction after prophylactic mastectomy in women with BRCA mutations from eight countries.
methodsWomen with a BRCA1 or BRCA2 mutation were questioned regarding their cancer preventive practices. Information was recorded on prophylactic mastectomy and breast reconstruction.
resultsA total of 1,635 women with a BRCA1 or BRCA2 mutation who elected to undergo prophylactic mastectomy from eight countries were included. A total of 1,137 women (69.5%) had breast reconstruction after prophylactic mastectomy. A total of 58.7% of women over the age of 45 years at the time of prophylactic mastectomy had breast reconstruction compared to 77.6% of women 35 years of age or younger [odds ratio (OR) 0.36, 95% confidence interval (CI) 0.26-0.50, p < 0.001]. In addition, 62.9% of women with a breast cancer diagnosis (contralateral prophylactic mastectomy) had breast reconstruction after prophylactic mastectomy compared to 79.7% of women without a previous breast cancer diagnosis (OR 0.48, 95% CI 0.38-0.61, p < 0.001). A total of 66.9% of women from Canada had breast reconstruction after mastectomy compared to 71.9% of American women (OR 0.75, 95% CI 0.59-0.96, p = 0.02).
conclusionsThe majority of women elect for breast reconstruction after prophylactic mastectomy. However, younger women and those without a previous diagnosis of breast cancer are more likely to have breast reconstruction than older women or those with a previous diagnosis of cancer.
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