ArticleStem cell research & therapy2013
Pre-conditioned mesenchymal stem cells: a better way for cell-based therapy.
Article in Stem cell research & therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 55 citations in OpenAlex.
- Role of hydrogen peroxide preconditioning in mesenchymal stem cell-mediated heart regeneration: Molecular insights.World journal of cardiology · 2025Review
- Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis.Journal of neuropathology and experimental neurology · 2025Review
- Small extracellular vesicles enhance the survival of Sca-1+ cardiac stem cells against ROS-induced ischemic-reoxygenation injury in vitro.Biological research · 2025Article
- Immunological Safety Evaluation of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells in Mice.Stem cells international · 2025Article
- Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages.World journal of stem cells · 2024Article
- Mesenchymal stromal cell-derived secretome-based therapy for neurodegenerative diseases: overview of clinical trials.Stem cell research & therapy · 2023Review
- MicroRNA-206 down-regulated human umbilical cord mesenchymal stem cells alleviate cognitive decline in D-galactose-induced aging mice.Cell death discovery · 2022Article
- Applying stem cell therapy in intractable diseases: a narrative review of decades of progress and challenges.Stem cell investigation · 2022Review
- Dimethyl fumarate prevents cytotoxicity and apoptosis mediated by oxidative stress in human adipose-derived mesenchymal stem cells.Molecular biology reports · 2021Article
- Stem Cell-Based Therapies for Parkinson Disease.International journal of molecular sciences · 2020Review
- Tetramethylpyrazine enhanced the therapeutic effects of human umbilical cord mesenchymal stem cells in experimental autoimmune encephalomyelitis mice through Nrf2/HO-1 signaling pathway.Stem cell research & therapy · 2020Article
- Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy.Cell death & disease · 2020Article
- Mesenchymal Stem Cells Reconditioned in Their Own Serum Exhibit Augmented Therapeutic Properties in the Setting of Acute Respiratory Distress Syndrome.Stem cells translational medicine · 2019Article
- Therapeutic Potential of Human Amniotic Epithelial Cells on Injuries and Disorders in the Central Nervous System.Stem cells international · 2019Review
- Dual Preconditioning: A Novel Strategy to Withstand Mesenchymal Stem Cells against Harsh Microenvironments.Advanced pharmaceutical bulletin · 2018Article
- Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro.Stem cell research & therapy · 2017Article
- OCT4 expression mediates partial cardiomyocyte reprogramming of mesenchymal stromal cells.PloS one · 2017Article
- Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells.Cell death & disease · 2016Article
- Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells.Molecular medicine reports · 2016Article
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3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Ischemic heart disease is the major cause of death globally, and a recently developed stem cell transplantation is a promising therapy for myocardial infarction. Mesenchymal stem cells (MSCs) exist in a wide range of tissues, and their differentiation potential and immunoregulatory capacity make them a more optimal candidate for regenerative medicine. However, the poor survival and low differentiation efficiency of the donor cells in the infarcted myocardium challenged therapeutic efficacy of MSC transplantation. To this end, many researchers have focused on improving the microenvironments of MSCs before and after transplantation and on trying to figure out the mechanisms. A recent study by Boopathy and colleagues reported the pro-cardiovascular differentiation effect of oxidative stress on cultured MSCs and the underlying signal pathways, leading to the notion that MSCs pre-conditioned with oxidative reagents promote cardiac differentiation efficiency of MSCs and may result in better clinical effect for ischemic heart diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.