ArticleMuscles, ligaments and tendons journal2012
The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?
Article in Muscles, ligaments and tendons journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03514537 (Use of Autologous Stem/Stromal Cellular Stromal Vascular Fraction), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Autologous Stem/Stromal Cellular Stromal Vascular Fraction (cSVF) In Cases Of Frailty and Aging Processes Using Autologous Stem-Stromal Cell Infusion in Patients With Aging Frailty And Wellness
Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Extracellular Vesicles-Induced Cell Homing and Odontogenesis via microRNA Signaling for Dentin Regeneration.International journal of molecular sciences · 2025Article
- Mesenchymal stem cells: An efficient cell therapy for tendon repair (Review).International journal of molecular medicine · 2023Review
- Amniotic Mesenchymal-Derived Extracellular Vesicles and Their Role in the Prevention of Persistent Post-Breeding Induced Endometritis.International journal of molecular sciences · 2023Article
- Exosome-Based Cell Homing and Angiogenic Differentiation for Dental Pulp Regeneration.International journal of molecular sciences · 2022Article
- Extracellular vesicles from equine mesenchymal stem cells decrease inflammation markers in chondrocytes in vitro.Equine veterinary journal · 2022Article
- Basic Research on Tendon Repair: Strategies, Evaluation, and Development.Frontiers in medicine · 2021Review
- Extracellular vesicles from human mesenchymal stem cells expedite chondrogenesis in 3D human degenerative disc cell cultures.Stem cell research & therapy · 2020Article
- Umbilical cord-derived Wharton's jelly for regenerative medicine applications.Journal of orthopaedic surgery and research · 2020Article
- Freeze-Dried Extracellular Vesicles From Adipose-Derived Stem Cells Prevent Hypoxia-Induced Muscle Cell Injury.Frontiers in cell and developmental biology · 2020Article
- Current Progress in Tendon and Ligament Tissue Engineering.Tissue engineering and regenerative medicine · 2019Review
- First Characterization of Human Amniotic Fluid Stem Cell Extracellular Vesicles as a Powerful Paracrine Tool Endowed with Regenerative Potential.Stem cells translational medicine · 2017Article
- Altered expression of G1/S phase cell cycle regulators in placental mesenchymal stromal cells derived from preeclamptic pregnancies with fetal-placental compromise.Cell cycle (Georgetown, Tex.) · 2017Article
- Article
- Advances in the Use of Stem Cells in Veterinary Medicine: From Basic Research to Clinical Practice.Scientifica · 2016Review
- Cellular phenotype and extracellular vesicles: basic and clinical considerations.Stem cells and development · 2014Article
- Paracrine effects of stem cells in wound healing and cancer progression (Review).International journal of oncology · 2014Review
- The influence of static magnetic fields on canine and equine mesenchymal stem cells derived from adipose tissue.In vitro cellular & developmental biology. Animal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tendon injuries represent even today a challenge as repair may be exceedingly slow and incomplete. Regenerative medicine and stem cell technology have shown to be of great promise. Here, we will review the current knowledge on the mechanisms of the regenerative potential of mesenchymal stem cells (MSCs) obtained from different sources (bone marrow, fat, cord blood, placenta). More specifically, we will devote attention to the current use of MSCs that have been used experimentally and in limited numbers of clinical cases for the surgical treatment of subchondral-bone cysts, bone-fracture repair and cartilage repair. Based on the recently emerging role in regenerative mechanisms of soluble factors and of extracellular vesicles, we will discuss the potential of non-cellular therapies in horse tendon injuries.
Indexed as
Identifiers
23738299PMC3666529W2096852436What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.