ArticleISRN veterinary science2011
Origins of injection-site sarcomas in cats: the possible role of chronic inflammation-a review.
Article in ISRN veterinary science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Apoptosis inhibitor of macrophage (AIM/CD5L) as a potential immunomodulator in feline injection-site sarcoma: a hypothesis on tumor-macrophage interactions.The veterinary quarterly · 2026Review
- A Rare Case of Malignant Plasmacytoma at a Previous Injection Site in a Cat.Veterinary sciences · 2026Article
- Histological and Immunohistochemical Findings of an Extremely Rare Multi-Organ Metastasis of Fibrosarcoma in a Holstein Cow.Veterinary medicine and science · 2025Article
- Metallothionein expression in feline injection site fibrosarcomas.BMC veterinary research · 2023Article
- Soft tissue sarcoma at the site of a previous laparoscopic-assisted gastropexy in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2021Article
- What Animal Cancers teach us about Human Biology.Theranostics · 2021Review
- Unusual presentation of gouty tophus in the liver with subsequent appearance in the same site of HCC: a correlate diagnosis? Case report.World journal of surgical oncology · 2019Article
- Soft tissue sarcoma affecting the right shoulder of a man with paraplegia from a remote traumatic spinal cord injury: a case report.Spinal cord series and cases · 2018Article
- Ten Things You Might Not Know about Iron Oxide Nanoparticles.Radiology · 2017Review
- Cytogenomics of Feline Cancers: Advances and Opportunities.Veterinary sciences · 2015Review
- Fibrosarcoma arising from gouty tophi: report of a unique case and review of literature.International journal of clinical and experimental pathology · 2015Review
- Subcutaneous fluid port-associated soft tissue sarcoma in a cat.Journal of feline medicine and surgery · 2013Article
- 2013 AAFP Feline Vaccination Advisory Panel Report.Journal of feline medicine and surgery · 2013Article
- Malignant nerve sheath tumor infiltrating the epididymis of an inguinal cryptorchid testis in a domestic shorthair cat.JFMS open reportsArticle
- Cutaneous non-epitheliotropic T-cell lymphoma associated with a fracture site in a cat.JFMS open reportsArticle
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The etiology of feline injection-site sarcomas remains obscure. Sarcomas and other tumors are known to be associated with viral infections in humans and other animals, including cats. However, the available evidence suggests that this is not the case with feline injection-site sarcomas. These tumors have more in common with sarcomas noted in experimental studies with laboratory animals where foreign materials such as glass, plastics, and metal are the causal agent. Tumors arising with these agents are associated with chronic inflammation at the injection or implantation sites. Similar tumors have been observed, albeit infrequently, at microchip implantation sites, and these also are associated with chronic inflammation. It is suggested that injection-site sarcomas in cats may arise at the administration site as a result of chronic inflammation, possibly provoked by adjuvant materials, with subsequent DNA damage, cellular transformation, and clonal expansion. However, more fundamental research is required to elucidate the mechanisms involved.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.