ReviewOxidative medicine and cellular longevity2013
Red orange: experimental models and epidemiological evidence of its benefits on human health.
Review in Oxidative medicine and cellular longevity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 133 citations in OpenAlex.
- Effectiveness of "Moro" Blood OrangeNutrients · 2022Trial
- Melatonin Boosts the Phytochemical Profile of Blood Oranges, Enhancing (Poly)phenol and Endogenous Melatonin Content, Through Pre- and Postharvest Treatments.Journal of pineal research · 2025Article
- Moro Orange (International journal of molecular sciences · 2025Article
- Article
- Brassinosteroid preharvest treatments as a useful tool to increase crop yield and red colour in blood orange fruits.Frontiers in plant science · 2025Article
- Effect of Blood Orange (Antioxidants (Basel, Switzerland) · 2024Article
- Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study.Nutrition journal · 2024Article
- The Effects of Antioxidant Supplementation on Soccer Performance and Recovery: A Critical Review of the Available Evidence.Nutrients · 2024Review
- A high-quality chromosome-scale genome assembly of blood orange, an important pigmented sweet orange variety.Scientific data · 2024Article
- Research Progress of Natural Products with the Activity of Anti-nonalcoholic Steatohepatitis.Mini reviews in medicinal chemistry · 2024Review
- Antioxidant Interactions between Citrus Fruit Carotenoids and Ascorbic Acid in New Models of Animal Cell Membranes.Antioxidants (Basel, Switzerland) · 2023Article
- Evaluation of Non-Alcoholic Beverages and the Risk Related to Consumer Health among the Romanian Population.Nutrients · 2023Observational
- Protective effects of red orange (Nutrition research and practice · 2023Article
- Diversity of Mycotoxins and Other Secondary Metabolites Recovered from Blood Oranges Infected byToxins · 2023Article
- β-carotene genetically-enriched lyophilized orange juice increases antioxidant capacity and reduces β-amyloid proteotoxicity and fat accumulation inFood chemistry. Molecular sciences · 2022Article
- Distribution, Antioxidant Capacity, Bioavailability and Biological Properties of Anthocyanin Pigments in Blood Oranges and Other Citrus Species.Molecules (Basel, Switzerland) · 2022Review
- Understanding Blood versus Blond Orange Consumption: A Cross-Cultural Study in Four Countries.Foods (Basel, Switzerland) · 2022Article
- Beneficial effects of citrus flavanones naringin and naringenin and their food sources on lipid metabolism: An update on bioavailability, pharmacokinetics, and mechanisms.The Journal of nutritional biochemistry · 2022Review
- Bioactive compounds, antioxidant activity and fruit quality evaluation of eleven blood orange cultivars.Journal of the science of food and agriculture · 2022Article
- Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, there has been increasing public interest in plant antioxidants, thanks to the potential anticarcinogenic and cardioprotective actions mediated by their biochemical properties. The red (or blood) orange (Citrus sinensis (L.) Osbeck) is a pigmented sweet orange variety typical of eastern Sicily (southern Italy), California, and Spain. In this paper, we discuss the main health-related properties of the red orange that include anticancer, anti-inflammatory, and cardiovascular protection activities. Moreover, the effects on health of its main constituents (namely, flavonoids, carotenoids, ascorbic acid, hydroxycinnamic acids, and anthocyanins) are described. The red orange juice demonstrates an important antioxidant activity by modulating many antioxidant enzyme systems that efficiently counteract the oxidative damage which may play an important role in the etiology of numerous diseases, such as atherosclerosis, diabetes, and cancer. The beneficial effects of this fruit may be mediated by the synergic effects of its compounds. Thus, the supply of natural antioxidant compounds through a balanced diet rich in red oranges might provide protection against oxidative damage under differing conditions and could be more effective than, the supplementation of an individual antioxidant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.