ArticlePloS one2013
Associations between handedness and cerebral lateralisation for language: a comparison of three measures in children.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Cerebrovascular function and cognition in childhood: a systematic review of transcranial Doppler studies.BMC neurology · 2014Pooled it
- Lifespan Trajectories of Asymmetry in White Matter Tracts.Human brain mapping · 2026Article
- The Association Between Laterality and Stroke Severity: A Cross-Sectional Study.Health science reports · 2026Article
- Cerebral Lateralization During Handwritten and Typed Word Generation: A Functional Transcranial Doppler Ultrasound Study in Left-Handers and Right-Handers.The European journal of neuroscience · 2025Observational
- Beta Spectral Power during Passive Listening in Preschool Children with Specific Language Impairment.Developmental neuroscience · 2025Article
- Discrepant expressive language lateralization in children and adolescents with epilepsy.Annals of clinical and translational neurology · 2022Article
- Broca's cerebral asymmetry reflects gestural communication's lateralisation in monkeys (eLife · 2022Article
- Article
- An updated investigation of the multidimensional structure of language lateralization in left- and right-handed adults: a test-retest functional transcranial Doppler sonography study with six language tasks.Royal Society open science · 2021Article
- A large-scale estimate on the relationship between language and motor lateralization.Scientific reports · 2020Article
- Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics.Brain : a journal of neurology · 2019Article
- Cerebral lateralisation during signed and spoken language production in children born deaf.Developmental cognitive neuroscience · 2019Article
- Stage 1 Registered Report: The relationship between handedness and language ability in children.Wellcome open research · 2019Article
- Stage 2 Registered Report: There is no appreciable relationship between strength of hand preference and language ability in 6- to 7-year-old children.Wellcome open research · 2019Article
- Triplets, birthweight, and handedness.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Resounding failure to replicate links between developmental language disorder and cerebral lateralisation.PeerJ · 2018Article
- Atypical speech lateralization in adults with developmental coordination disorder demonstrated using functional transcranial Doppler ultrasound.Journal of neuropsychology · 2017Article
- The Relationship between Handedness and Mathematics Is Non-linear and Is Moderated by Gender, Age, and Type of Task.Frontiers in psychology · 2017Article
- Lateralization of ERPs to speech and handedness in the early development of Autism Spectrum Disorder.Journal of neurodevelopmental disorders · 2017Article
- Hemispheric speech lateralisation in the developing brain is related to motor praxis ability.Developmental cognitive neuroscience · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
Abstract
It has been known for many years that hand preference is associated with cerebral lateralisation for language, but the relationship is weak and indirect. It has been suggested that quantitative measures of differential hand skill or reaching preference may provide more valid measures than traditional inventories, but to date these have not been validated against direct measures of cerebral lateralisation. We investigated the associations of three different handedness assessments; 1) a hand preference inventory, 2) a measure of relative hand skill, and 3) performance on a reaching task; with cerebral lateralisation for language function as derived from functional transcranial Doppler ultrasound during a language production task, in a group of 57 typically developing children aged from 6 to 16 years. Significant correlations between cerebral lateralisation for language production and handedness were found for a short version of the inventory and for performance on the reaching task. However, confidence intervals for the correlations overlapped and no one measure emerged as clearly superior to the others. The best handedness measures accounted for only 8-16% of the variance in cerebral lateralisation. These findings indicate that researchers should not rely on handedness as an indicator of cerebral lateralisation for language. They also imply that lateralisation of language and motor functions in the human brain show considerable independence from one another.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.