ArticleEvidence-based complementary and alternative medicine : eCAM2013
Brain responses to acupuncture are probably dependent on the brain functional status.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Prolonged repeated acupuncture stimulation induces habituation effects in pain-related brain areas: an FMRI study.PloS one · 2014Trial
- Potential mechanisms of acupuncture for neuropathic pain based on somatosensory system.Frontiers in neuroscience · 2022Review
- Differences in functional brain alterations driven by right or left facial nerve efferent dysfunction: Evidence from early Bell's palsy.Quantitative imaging in medicine and surgery · 2019Article
- Longitudinal Changes in Functional Connectivity of the Caudate Is Associated With Recovery From Bell's Palsy.Frontiers in aging neuroscience · 2019Article
- Disrupted functional connectivity of striatal sub-regions in Bell's palsy patients.NeuroImage. Clinical · 2017Article
- Neurobiological Mechanism of Acupuncture for Relieving Visceral Pain of Gastrointestinal Origin.Gastroenterology research and practice · 2017Review
- Sensorimotor Cortical Neuroplasticity in the Early Stage of Bell's Palsy.Neural plasticity · 2017Article
- The Status of the Quality Control in Acupuncture-Neuroimaging Studies.Evidence-based complementary and alternative medicine : eCAM · 2016Review
- Effect of Acupuncture on Functional Connectivity of Anterior Cingulate Cortex for Bell's Palsy Patients with Different Clinical Duration.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Specific Correlation between the Hegu Point (LI4) and the Orofacial Part: Evidence from an fMRI Study.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Acupuncture-induced changes in functional connectivity of the primary somatosensory cortex varied with pathological stages of Bell's palsy.Neuroreport · 2014Article
- Mechanisms of acupuncture-electroacupuncture on persistent pain.Anesthesiology · 2014Review
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, neuroimaging studies of acupuncture have explored extensive aspects of brain responses to acupuncture in finding its underlying mechanisms. Most of these studies have been performed on healthy adults. Only a few studies have been performed on patients with diseases. Brain responses to acupuncture in patients with the same disease at different pathological stages have not been explored, although it may be more important and helpful in uncovering its underlying mechanisms. In the present study, we used fMRI to compare brain responses to acupuncture in patients with Bell's palsy at different pathological stages with normal controls and found that the brain response to acupuncture varied at different pathological stages of Bell's palsy. The brain response to acupuncture decreased in the early stages, increased in the later stages, and nearly returned to normal in the recovered group. All of the changes in the brain response to acupuncture could be explained as resulting from the changes in the brain functional status. Therefore, we proposed that the brain response to acupuncture is dependent on the brain functional status, while further investigation is needed to provide more evidence in support of this proposition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.