ArticleJournal of cancer epidemiology2013
Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors.
Article in Journal of cancer epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 602 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Multi-Genetic Test for the Diagnosis of Indeterminate Thyroid Nodules
Validation of the Diagnostic Accuracy of the Electronic Nose in the Detection of Thyroid Cancer
Who cites it
602 citing papers in PubMed, 6 syntheses or guidelines pooled it, 1,285 citations in OpenAlex.
- Dietary Pattern and Risk of Thyroid Cancer: A Systematic Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Pooled it
- Association between prediabetes and thyroid cancer risk: A meta-analysis.Biomolecules & biomedicine · 2025Pooled it
- Performance Evaluation of Deep Learning for the Detection and Segmentation of Thyroid Nodules: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Size Increment During Surveillance in Papillary Thyroid Cancer: Evidence Synthesis and Dose-Response Meta-Analysis.Cancer reports (Hoboken, N.J.) · 2025Pooled it
- The risk of central nodal metastasis based on prognostic factors of the differentiated thyroid carcinoma: a systematic review and meta-analysis study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Pooled it
- Prevalence and Impact of BRAF mutation in patients with concomitant papillary thyroid carcinoma and Hashimoto's thyroiditis: a systematic review with meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Gene network and biological pathways associated with susceptibility to differentiated thyroid carcinoma.Scientific reports · 2021Trial
- Association Between Collagen-Based Hemostatic Patch Use and Patient-Reported Recovery After Bilateral Thyroidectomy: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- The incidence and perinatal outcomes of pregnancy-associated thyroid cancer: an Australian population-based study.Journal of the Endocrine Society · 2026Article
- Development and validation of an ultrasound-based deep learning radiomics nomogram for risk assessment of lymph node metastasis in papillary thyroid microcarcinoma.Quantitative imaging in medicine and surgery · 2026Article
- A nomogram predicting dysphagia risk after adjuvant iodine-131 therapy in patients with papillary thyroid carcinoma.Nuclear medicine communications · 2026Article
- Increased Risk of Thyroid Cancer in Patients with Graves' Disease and Thyroid Nodules: A Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2026Article
- Investigation and analysis of rumination level and its associated factors in patients with thyroid cancer.Medicine · 2026Article
- Article
- Frequency of Thyroid Cancer in Multinodular Goiter Undergoing Thyroidectomy in Tertiary Care Centre in Pakistan: A Cross-Sectional Analysis.Health science reports · 2026Article
- Risk Stratification of Indeterminate Thyroid Nodules (TIR3A vs. TIR3B): Impact of NIFTP Reclassification in a Surgical Cohort.Cancers · 2026Article
- Article
- First successful radiofrequency ablation for papillary thyroid microcarcinoma in Indonesia: a case report.International journal of surgery case reports · 2026Article
- Natural product-based interventions for thyroid disorders: mechanisms and applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- The Role of Mean Platelet Volume (MPV) in Thyroid Cancers: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Review
542 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. In the last decades, thyroid cancer incidence has continuously and sharply increased all over the world. This review analyzes the possible reasons of this increase. Summary. Many experts believe that the increased incidence of thyroid cancer is apparent, because of the increased detection of small cancers in the preclinical stage. However, a true increase is also possible, as suggested by the observation that large tumors have also increased and gender differences and birth cohort effects are present. Moreover, thyroid cancer mortality, in spite of earlier diagnosis and better treatment, has not decreased but is rather increasing. Therefore, some environmental carcinogens in the industrialized lifestyle may have specifically affected the thyroid. Among potential carcinogens, the increased exposure to medical radiations is the most likely risk factor. Other factors specific for the thyroid like increased iodine intake and increased prevalence of chronic autoimmune thyroiditis cannot be excluded, while other factors like the increasing prevalence of obesity are not specific for the thyroid. Conclusions. The increased incidence of thyroid cancer is most likely due to a combination of an apparent increase due to more sensitive diagnostic procedures and of a true increase, a possible consequence of increased population exposure to radiation and to other still unrecognized carcinogens.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.