ReviewCurrent hypertension reports2013
Primary hypertension in children and adolescents is an immuno-metabolic disease with hemodynamic consequences.
Review in Current hypertension reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early kidney damage in children and adolescents with primary arterial hypertension: a systematic review.European journal of pediatrics · 2025Pooled it
- Oxidative Stress and Endothelial Dysfunction: The Pathogenesis of Pediatric Hypertension.International journal of molecular sciences · 2025Review
- Beyond Cardiometabolic: Health Disorders Risk in Metabolically Healthy Obese Children - A Systematic Review and Meta-Analysis of 19,119 Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Metabolic syndrome therapy in pediatric age - between classic and modern. From diets to pipeline drugs.Frontiers in nutrition · 2024Review
- Study on the relationship between body mass index and blood pressure indices in children aged 7-17 during COVID-19.Frontiers in public health · 2024Article
- Association of serum transforming growth factor βEuropean journal of pediatrics · 2023Article
- Distribution and maturation state of peripheral blood dendritic cells in children with primary hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Association Between Extraversion Personality With the Blood Pressure Level in Adolescents.Frontiers in cardiovascular medicine · 2022Article
- Clinical follow-up study of 166 cases of children with hypertension.Translational pediatrics · 2021Article
- Does Arterial Hypertension Affect Plasma Levels of Matrix Metalloproteinases and Their Tissue Inhibitors in Patients with Stable Coronary Artery Disease? A Preliminary Study.Cardiology research and practice · 2019Article
- Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for young hypertensive men.Analytica chimica acta · 2015Article
- Expression of Adiponectin Receptors on Peripheral Blood Leukocytes of Hypertensive Children Is Associated with the Severity of Hypertension.BioMed research international · 2015Article
- Autonomic nervous system dysregulation in pediatric hypertension.Current hypertension reports · 2014Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the rise in obesity epidemic primary hypertension (PH) is now one of the most common chronic diseases in adolescence. In contrast to hypertensive adults, hypertensive children usually are not exposed to other comorbidities such as diabetes, chronic kidney disease and atherosclerosis. Thus, PH in children and adolescents can be treated as the early stage of development of cardiovascular disease. There is increasing amount of data indicating that PH is not only hemodynamic phenomenon but a complex syndrome involving disturbed activity of sympathetic nervous system, metabolic abnormalities and activation of innate and adaptive immune system. We discuss results of the studies on clinical, metabolic and immunological phenotype of hypertensive children, associations between metabolic and immunological abnormalities with target organ damage and results of antihypertensive treatment.
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