ReviewEuropean journal of applied physiology2014
Blood pressure regulation IX: cerebral autoregulation under blood pressure challenges.
Review in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
113 citing papers in PubMed.
- Dietary nitrate supplementation effect on dynamic cerebral autoregulation in normoxia and acute hypoxia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Trial
- Hemodynamic Stability to Surface Warming and Cooling During Sustained and Continuous Simulated Hemorrhage in Humans.Shock (Augusta, Ga.) · 2016Trial
- Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: the effect of midodrine.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Trial
- Loss of cerebral autoregulation drives abnormal perfusion patterns after stroke.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Cerebral protection strategies in aortic arch surgery: a review of techniques and outcomes.Annals of cardiothoracic surgery · 2026Article
- Attenuated aortic-cerebral pulsatile transmission with posture-related increases in stroke volume in healthy young adults.European journal of applied physiology · 2026Article
- Blood Pressure Variability is Associated With Lower Cognitive Function: An Elderly Cohort Study in Hong Kong.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Accounting for squared coherence marginally improves the discriminative power of frequency domain cerebral autoregulation markers in surgical aortic valve replacement patients.Medical & biological engineering & computing · 2026Article
- [Dynamic changes and physiological regulation of common carotid artery blood flow during general anesthesia in elderly patients: a prospective study].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Brain strain: Blood flow and metabolism in environmental extremes.Experimental physiology · 2026Review
- Temporal Dynamics of Perioperative Redox Balance and Its Association with Postoperative Delirium After Cardiac Surgery.Antioxidants (Basel, Switzerland) · 2026Article
- Imaging photoplethysmography reveals differences in the reactions of cerebral and systemic hemodynamics to infusion of vasoactive drugs.Frontiers in physiology · 2026Article
- Acid-Base Status and Cerebral Oxygenation in Neonates: A Systematic Qualitative Review of the Literature.Children (Basel, Switzerland) · 2025Review
- Prehospital Postintubation Hypotension and Survival in Severe Traumatic Brain Injury.JAMA network open · 2025Observational
- Age-Related Alterations of Cerebral Autoregulation.Life (Basel, Switzerland) · 2025Review
- Aggregated postpartum cerebral autoregulatory curves in normotensive individuals, preeclampsia with severe features, and superimposed preeclampsia with severe features.Physiological measurement · 2025Observational
- Linking Neurocardiovascular Responses in the Active Stand Test to Adverse Outcomes: Insights from the Irish Longitudinal Study on Ageing (TILDA).Sensors (Basel, Switzerland) · 2025Article
- Toll-Like Receptor 4-Mediated Neuroinflammation: Updates on Pathological Roles and Therapeutic Strategies in Chronic Cerebral Hypoperfusion.Molecular neurobiology · 2025Review
- Directional sensitivity analysis of the cerebral pressure-flow relationship during normothermia and moderate hyperthermia.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Characterizing Brain-Cardiovascular Aging Using Multiorgan Imaging and Machine Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
53 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure. The last four decades has seen dramatic advances in understanding CA physiology, and the role that CA might play in the causation and progression of disease processes that affect the cerebral circulation such as stroke. However, the translation of these basic scientific advances into clinical practice has been limited by the maintenance of old constructs and because there are persistent gaps in our understanding of how this vital vascular mechanism should be quantified. In this review, we re-evaluate relevant studies that challenge established paradigms about how the cerebral perfusion pressure and blood flow are related. In the context of blood pressure being a major haemodynamic challenge to the cerebral circulation, we conclude that: (1) the physiological properties of CA remain inconclusive, (2) many extant methods for CA characterisation are based on simplistic assumptions that can give rise to misleading interpretations, and (3) robust evaluation of CA requires thorough consideration not only of active vasomotor function, but also the unique properties of the intracranial environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.