Evidence map›Paper›PMID 23736883›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2014

Vagus somatosensory evoked potentials are delayed in Alzheimer's disease, but not in major depression.

Thomas Polak, Thomas Dresler, Julia B M Zeller, Bodo Warrings, Peter Scheuerpflug, Andreas J Fallgatter, Jürgen Deckert, Florian G Metzger

Abstract read
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In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Article
  5. The gut microbiota to the brain axis in the metabolic control.Reviews in endocrine & metabolic disorders · 2019
    Review
  6. Observational
  7. The relation of SMI and the VSEP in a risk sample for neurodegenerative disorders.Journal of neural transmission (Vienna, Austria : 1996) · 2015
    Article
  8. PPARγ upregulation induced by vagus nerve stimulation exerts anti-inflammatory effect in cerebral ischemia/reperfusion rats.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  9. Reward, memory and prediction of treatment response in affective disorders.European archives of psychiatry and clinical neuroscience · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Thomas PolakDepartment of Psychiatry, Psychosomatics and Psychotherapy, University Clinic Wuerzburg, Fuechsleinstrasse 15, 97080, Wuerzburg, Germany, Polak_T@klinik.uni-wuerzburg.de.
Thomas Dresler
Julia B M Zeller
Bodo Warrings
Peter Scheuerpflug
Andreas J Fallgatter
Jürgen Deckert
Florian G Metzger
Social Neuroscience Lab · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Alzheimer's disease (AD), the degeneration of brainstem nuclei is different from major depression (MD). Thus, vagus somatosensory evoked potentials (VSEP) proposed for the functional assessment of brainstem nuclei should show prolonged latencies in AD but not in MD. In 55 AD patients, 57 MD patients and two age-matched control groups evoked potentials were recorded upon stimulation of the auricular branch of the vagus nerve. In the AD, not in the MD group, latencies were significantly longer as compared to controls. Thus, the method of VSEP could contribute to the important differential diagnosis of AD and MD in elderly patients.

Indexed as

Vagus Nerve StimulationAgedAlzheimer DiseaseAmyloid beta-PeptidesAnalysis of VarianceCase-Control StudiesEvoked Potentials, SomatosensoryFemaleHumansMajor Depressive DisorderMaleMiddle AgedPsychiatric Status Rating ScalesReaction TimeSensitivity and SpecificityAmyloid beta-Peptides

Identifiers

PMID23736883
OpenAlexW2081959476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.