Trial reportNature communications2013
Aerosol transmission is an important mode of influenza A virus spread.
Trial report in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
154 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Comparative effectiveness of N95, surgical or medical, and non-medical facemasks in protection against respiratory virus infection: A systematic review and network meta-analysis.Reviews in medical virology · 2022Pooled it
- Pooled it
- Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19.Respiration; international review of thoracic diseases · 2020Guideline
- Review Article: Influenza Transmission on Aircraft: A Systematic Literature Review.Epidemiology (Cambridge, Mass.) · 2016Pooled it
- Hand hygiene and risk of influenza virus infections in the community: a systematic review and meta-analysis.Epidemiology and infection · 2014Pooled it
- Minimal transmission in an influenza A (H3N2) human challenge-transmission model within a controlled exposure environment.PLoS pathogens · 2020Trial
- The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel.BMC infectious diseases · 2016Trial
- Inferring influenza dynamics and control in households.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Increased hand washing reduces influenza virus surface contamination in Bangkok households, 2009-2010.Influenza and other respiratory viruses · 2014Trial
- Andes Virus: From Transmission Dynamics to Pandemic Potential.European journal of clinical investigation · 2026Review
- Associations of Indoor Nighttime Ventilation with the Relative Abundances of Typical Pathogenic Bacteria and Fungi in Settled Dusts from Floor, Desk, and Bed of University Dormitories.Microorganisms · 2026Article
- Climatic Influence on COVID-19: Investigating the Role of Temperature and Humidity in the Spread of the Omicron Variant.GeoHealth · 2026Article
- Pre-Exposure Intranasal Treatment with Neomycin Sulfate Reduces Transmission of Influenza B Virus.Antibiotics (Basel, Switzerland) · 2026Article
- Toxicological interactions between biotic and abiotic components of indoor air: Mold and air fresheners.Journal of hazardous materials · 2026Article
- Evaluating modes of influenza transmission (EMIT-2): Insights from lack of transmission in a controlled transmission trial with naturally infected donors.PLoS pathogens · 2026Article
- Insights into the mechanisms of infection transmission via inanimate surfaces.Frontiers in microbiology · 2026Review
- Spray-Dried Inhalable Favipiravir Dry Powder Formulation for Influenza Therapy: Preparation andCurrent drug delivery · 2026Article
- Evaluating Modes of Influenza Transmission (EMIT-2): Insights from a Controlled Human Influenza Virus Infection Transmission Trial (CHIVITT).medRxiv : the preprint server for health sciences · 2025Article
- Rapid inactivation of aerosolised influenza virus using low-concentration gaseous hypochlorous acid.Scientific reports · 2025Article
- Effective Aerosol Inoculation of Dose-Escalated Seasonal Influenza H3N2 Virus in Controlled Human Infection Model.medRxiv : the preprint server for health sciences · 2025Article
94 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Influenza A viruses are believed to spread between humans through contact, large respiratory droplets and small particle droplet nuclei (aerosols), but the relative importance of each of these modes of transmission is unclear. Volunteer studies suggest that infections via aerosol transmission may have a higher risk of febrile illness. Here we apply a mathematical model to data from randomized controlled trials of hand hygiene and surgical face masks in Hong Kong and Bangkok households. In these particular environments, inferences on the relative importance of modes of transmission are facilitated by information on the timing of secondary infections and apparent differences in clinical presentation of secondary infections resulting from aerosol transmission. We find that aerosol transmission accounts for approximately half of all transmission events. This implies that measures to reduce transmission by contact or large droplets may not be sufficient to control influenza A virus transmission in households.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.