Evidence map›Paper›PMID 23736375›Full record

ArticleEuropean radiology2013

Multi-sequence whole-brain intracranial vessel wall imaging at 7.0 tesla.

Anja G van der Kolk, Jeroen Hendrikse, Manon Brundel, Geert J Biessels, Ewoud J Smit, Fredy Visser, Peter R Luijten, Jaco J M Zwanenburg

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
    Pooled it
  2. Trial
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  10. Black-Blood Contrast in Cardiovascular MRI.Journal of magnetic resonance imaging : JMRI · 2022
    Review
  11. Intracranial vessel wall lesions on 7T MRI and MRI features of cerebral small vessel disease: The SMART-MR study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  12. TFrontiers in neuroscience · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anja G van der KolkDepartment of Radiology, University Medical Center Utrecht, Post Box 85500, 3508 GA, Utrecht, The Netherlands, A.G.vanderKolk@umcutrecht.nl.
Jeroen Hendrikse
Manon Brundel
Geert J Biessels
Ewoud J Smit
Fredy Visser
Peter R Luijten
Jaco J M Zwanenburg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIntracranial vessel wall magnetic resonance imaging (MRI) may improve the diagnosis of vessel wall abnormalities. Current methods are hampered by limited coverage and few contrast weightings. We present a multi-sequence protocol with whole-brain coverage for vessel wall imaging on 7.0-T MRI.

methodsA modified magnetisation-preparation inversion recovery turbo-spin-echo (MPIR-TSE) sequence was used to obtain proton density (PD)-, T1-, and T2-weighting with 190-mm whole-brain coverage. Three observers independently scored the visibility of arterial vessel walls in five healthy volunteers, and compared the conspicuity and image contrast of all sequences. Clinical applicability was demonstrated in 17 patients with cerebrovascular disease.

resultsConspicuity was good for all acquisitions, with best scores for the original limited-coverage sequence, followed by whole-brain coverage T2-, PD- and T1-weighted sequences, respectively. Mean vessel wall/background MR signal intensity ratios for all whole-brain sequences were similar, with higher scores for the limited-coverage MPIR-TSE sequence. Signal intensity ratios were highest in patients, for the whole-brain T1-weighted sequence.

conclusionsThe whole-brain multi-sequence vessel wall protocol can assess intracranial arterial vessel walls with full brain coverage, for different image contrast weightings. These sequences could eventually characterise intracranial vessel wall abnormalities similar to current techniques for assessing carotid artery plaques. KEY POINTS: - Intracranial vessel wall imaging using MRI improves diagnosis of cerebrovascular diseases. - Conventional 7-T MRI sequences cannot image the whole cerebral arterial tree. - New whole-brain 7-T MRI sequences compare favourably with smaller-coverage sequences. - These whole-brain sequences can demonstrate the entire cerebral arterial tree. - These sequences should help in the diagnosis of vessel wall abnormalities.

Indexed as

Image Processing, Computer-AssistedAdultArtifactsBrainBrain IschemiaCircle of WillisEcho-Planar ImagingFemaleFollow-Up StudiesHealthy VolunteersHumansMaleProspective StudiesReproducibility of ResultsROC CurveYoung Adult

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.