Trial reportThorax2013
The effectiveness of a structured education pulmonary rehabilitation programme for improving the health status of people with moderate and severe chronic obstructive pulmonary disease in primary care: the PRINCE cluster randomised trial.
Trial report in Thorax, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care.The Cochrane database of systematic reviews · 2022Pooled it
- Assessing heterogeneity of treatment effect analyses in health-related cluster randomized trials: A systematic review.PloS one · 2019Pooled it
- Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2017Pooled it
- Pulmonary rehabilitation for chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2015Pooled it
- Clinically important changes and adverse events with centre-based or home-based pulmonary rehabilitation in chronic respiratory disease: A systematic review and meta-analysis.Chronic respiratory diseasePooled it
- Minimal vs Specialized Exercise Equipment for Pulmonary Rehabilitation: A Randomized Clinical Trial.JAMA network open · 2025Trial
- PURE PRIME: Implementing PUlmonary REhabilitation in PRIMary carE: a protocol for a randomized controlled feasibility trial.Primary health care research & development · 2025Article
- Effects of Physical Exercise on Walking Distance and Functional Limitations in Patients with Chronic Dyspnea.Medicina (Kaunas, Lithuania) · 2025Article
- The Comprehensive Resilience-building psychosocial Intervention (CREST) for people with dementia in the community: a feasibility and acceptability study.Pilot and feasibility studies · 2024Article
- Article
- Immediate and One-Year Outcomes of an Asthma-Tailored Pulmonary Rehabilitation Programme in Overweight and Obese People with Difficult-to-Treat Asthma.Journal of asthma and allergy · 2024Article
- Defining Modern Pulmonary Rehabilitation. An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2021Article
- The feasibility of a Comprehensive Resilience-building psychosocial Intervention (CREST) for people with dementia in the community: protocol for a non-randomised feasibility study.Pilot and feasibility studies · 2020Article
- Do Chronic Obstructive Pulmonary Diseases (COPD) Self-Management Interventions Consider Health Literacy and Patient Activation? A Systematic Review.Journal of clinical medicine · 2020Review
- [Effectiveness of an educational program for respiratory rehabilitation of Chronic Obstructive Pulmonary Disease patients in Primary Care in improving the quality of life, symptoms, and clinical risk].Atencion primaria · 2018Article
- Outcomes of community-based and home-based pulmonary rehabilitation for pneumoconiosis patients: a retrospective study.BMC pulmonary medicine · 2018Article
- Relationship between self-efficacy, beliefs, and physical activity in inflammatory arthritis.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2016Article
- Pulmonary rehabilitation for COPD: are programs with minimal exercise equipment effective?Journal of thoracic disease · 2014Review
- Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effectiveness of a structured education pulmonary rehabilitation programme on the health status of people with chronic obstructive pulmonary disease (COPD).
designTwo-arm, cluster randomised controlled trial.
setting32 general practices in the Republic of Ireland.
participants350 participants with a diagnosis of moderate or severe COPD.
interventionExperimental group received a structured education pulmonary rehabilitation programme, delivered by the practice nurse and physiotherapist. Control group received usual care.
main outcome measureHealth status as measured by the Chronic Respiratory Questionnaire (CRQ) at baseline and at 12-14 weeks postcompletion of the programme.
resultsParticipants allocated to the intervention group had statistically significant higher mean change total CRQ scores (adjusted mean difference (MD) 1.11, 95% CI 0.35 to 1.87). However, the CI does not exclude a smaller difference than the one that was prespecified as clinically important. Participants allocated to the intervention group also had statistically significant higher mean CRQ Dyspnoea scores after intervention (adjusted MD 0.49, 95% CI 0.20 to 0.78) and CRQ Physical scores (adjusted MD 0.37, 95% CI 0.14 to 0.60). However, CIs for both the CRQ Dyspnoea and CRQ Physical subscales do not exclude smaller differences as prespecified as clinically important. No other statistically significant differences between groups were seen.
conclusionsA primary care based structured education pulmonary rehabilitation programme is feasible and may increase local accessibility to people with moderate and severe COPD.
trial registrationISRCTN52403063.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.