Evidence map›Paper›PMID 23735726›Full record

Trial reportDiabetes care2013

REDEEM: a pragmatic trial to reduce diabetes distress.

Lawrence Fisher, Danielle Hessler, Russell E Glasgow, Patricia A Arean, Umesh Masharani, Diana Naranjo, Lisa A Strycker

3 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 127 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 5 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02175732 nacompletednot on this mapstarted 2014, after this paper: background citation

Reducing Distress And Improving Glycemic Control In Adults With Type 1 Diabetes

TypeinterventionalSponsorUniversity of California, San FranciscoRan2014 to 2018Enrolled301ConditionsType 1 Diabetes MellitusArms'KnowIt', 'OnTrack'
NCT06887049 narecruitingnot on this mapstarted 2026, after this paper: background citation

ARISE: Achieving Routine Intervention and Screening for Emotional Health: Randomized Controlled Trial

TypeinterventionalSponsorUniversity of ChicagoRan2026 to 2028Enrolled1,250ConditionsType 2 Diabetes Mellitus (T2DM), Diabetes DistressArmsARISE Learning Community Diabetes Distress Screening and Intervention, ARISE Enhanced Care brief training
NCT06972251 nacompletednot on this mapstarted 2022, after this paper: background citation

Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes (TARDIS) - Photo Elicitation and Intervention

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2022 to 2025Enrolled34ConditionsDiabetes Mellitus, Type II, Type 2 Diabetes, Diabetes Distress, Self ManagementArmsTARDIS Photo Elicitation, TARDIS Intervention
3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 5 syntheses or guidelines pooled it, 269 citations in OpenAlex.

  1. Pooled it
  2. Education programmes for people with chronic kidney disease and diabetes.The Cochrane database of systematic reviews · 2024
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  16. Mediators and Moderators of Improvements in Medication Adherence.Health education & behavior : the official publication of the Society for Public Health Education · 2017
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67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lawrence FisherUniversity of California, San Francisco, San Francisco, California, USA. fisherl@fcm.ucsf.edu
Danielle Hessler
Russell E Glasgow
Patricia A Arean
Umesh Masharani
Diana Naranjo
Lisa A Strycker
University of California, San Francisco · USNational Cancer Institute · USOregon Research Institute · US

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAISSE, CHRISTIAN · 2003 to 2019
$21.8M
Reducing Dirstress and Improving Self-Care in DiabetesR01DK061937 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FISHER, LAWRENCE · 2003 to 2011
$5.6M
NIDDK NIH HHS DK061937NIDDK NIH HHS P30 DK063720NIDDK NIH HHS R01 DK061937
6 · The paper itself

Abstract

objectiveTo compare three interventions to reduce diabetes distress (DD) and improve self-management among non-clinically depressed adults with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND

methodsIn REDEEM, 392 adults with T2DM and DD were randomized to computer-assisted self-management (CASM), CASM plus DD-specific problem solving (CAPS), or a computer-administered minimal supportive intervention. Primary outcomes were Diabetes Distress Scale (DDS) total, the Emotional Burden (EB) and Regimen Distress (RD) DDS subscales, and diet, exercise, and medication adherence.

resultsSignificant and clinically meaningful reductions in DD (DDS, EB, and RD) and self-management behaviors occurred in all three conditions (P < 0.001), with no significant between-group differences. There was, however, a significant group × baseline distress interaction (P < 0.02), in which patients with high baseline RD in the CAPS condition displayed significantly larger RD reductions than those in the other two conditions. RD generated the most distress and displayed the greatest distress reduction as a result of intervention. The pace of DD reduction varied by patient age: older patients demonstrated significant reductions in DD early in the intervention, whereas younger adults displayed similar reductions later. Reductions in DD were accompanied by significant improvements in healthy eating, physical activity, and medication adherence, although not by change in HbA1c.

conclusionsDD is malleable and highly responsive to intervention. Interventions that enhance self-management also reduce DD significantly, but DD-specific interventions may be necessary for patients with high initial levels of DD. Future research should identify the minimal, most cost-effective interventions to reduce DD and improve self-management.

Indexed as

AdultAgedDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedSelf CareYoung Adult

Identifiers

PMID23735726
PMCPMC3747867
OpenAlexW2132631590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.