ArticleJournal of the American Society of Hypertension : JASH
Dietary potassium: a key mediator of the cardiovascular response to dietary sodium chloride.
Article in Journal of the American Society of Hypertension : JASH. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Sodium and Potassium Intake and Cardiovascular Disease in Older People: A Systematic Review.Nutrients · 2020Pooled it
- DASH Dietary Pattern and Cardiometabolic Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses.Nutrients · 2019Pooled it
- Associations between diet quality, blood pressure, and glucose levels among pregnant women in the Asian megacity of Jakarta.PloS one · 2020Trial
- Toward Nutrient-Rich Rice: Biofortification through Mineral Accumulation and Low Phytic Acid Content.Journal of agricultural and food chemistry · 2025Article
- Modifying Dietary Sodium and Potassium Intake: An End to the 'Salt Wars'?Hypertension (Dallas, Tex. : 1979) · 2024Review
- Changes in the Urinary Sodium-to-Potassium Ratio Are Associated with Blood Pressure Change in Older Japanese Adults: A 7-Year Longitudinal Study.Journal of clinical medicine · 2022Article
- The Yin-Yang Dynamics in Cardiovascular Pharmacogenomics and Personalized Medicine.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Activation of the Sympathetic Nervous System Promotes Blood Pressure Salt-Sensitivity in C57BL6/J Mice.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Review
- Relationship between indirect blood pressure and various stages of chronic kidney disease in cats.The Journal of veterinary medical science · 2018Article
- Short-Term High-Salt Diet Increases Corin Level to Regulate the Salt-Water Balance in Humans and Rodents.American journal of hypertension · 2018Article
- Dietary sodium, dietary potassium, and systolic blood pressure in US adolescents.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- An Appraisal of Methods Recently Recommended for Testing Salt Sensitivity of Blood Pressure.Journal of the American Heart Association · 2017Review
- Role of Dietary Components in Modulating Hypertension.Journal of clinical & experimental cardiology · 2016Article
- The Circadian Clock in the Regulation of Renal Rhythms.Journal of biological rhythms · 2015Review
- Article
- Use of Urine Biomarkers to Assess Sodium Intake: Challenges and Opportunities.Annual review of nutrition · 2015Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Potassium and sodium share a yin/yang relationship in the regulation of blood pressure (BP). BP is directly associated with the total body sodium and negatively correlated with the total body potassium. Epidemiologic, experimental, and clinical studies have shown that potassium is a significant regulator of BP and further improves cardiovascular outcomes. Hypertensive cardiovascular damage, stroke, and stroke-related death are accelerated by salt intake but might be curbed by increasing dietary potassium intake. The antihypertensive effect of potassium supplementation appears to occur through several mechanisms that include regulation of vascular sensitivity to catecholamines, promotion of natriuresis, limiting plasma renin activity, and improving endothelial function. In the absence of chronic kidney disease, the combined evidence suggests that a diet rich in potassium content serves a vasculoprotective function, particularly in the setting of salt-sensitive hypertension and prehypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.