Evidence map›Paper›PMID 23734973›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2013

Inhaled corticosteroid adherence and emergency department utilization among Medicaid-enrolled children with asthma.

George Rust, Shun Zhang, Joshua Reynolds

Open access · greenAbstract read
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Assessing asthma severity based on claims data: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2017
    Pooled it
  4. Trial
  5. Article
  6. Mental health, long-term medication adherence, and the control of asthma symptoms among persons exposed to the WTC 9/11 disaster.The Journal of asthma : official journal of the Association for the Care of Asthma · 2020
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Individual and county level predictors of asthma related emergency department visits among children on Medicaid: A multilevel approach.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017
    Article
  15. Article
  16. Article
  17. Article
  18. Is ketamine a lifesaving agent in childhood acute severe asthma?Therapeutics and clinical risk management · 2016
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George RustMorehouse School of Medicine, National Center for Primary Care, Atlanta, USA. grust@msm.edu
Shun Zhang
Joshua Reynolds
Morehouse School of Medicine · US

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
Research Desogn and Biostatistics CoreU54MD007588 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2012 to 2018
$24.8M
Women's Health Intervention StudyP20MD006881 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI AKINTOBI, TABIA HENRY · 2012 to 2016
$6.0M
Optimal & Equitable Care: Medicaid Data Research InfrastructureR24HS019470 · AHRQ · MOREHOUSE SCHOOL OF MEDICINE · PI RUST, GEORGE S · 2010 to 2010
$994k
AHRQ HHS 1R24HS019470AHRQ HHS R24 HS019470NIMHD NIH HHS 2S21MD000101NIMHD NIH HHS P20 MD006881NIMHD NIH HHS S21 MD000101NIMHD NIH HHS U54 MD007588
6 · The paper itself

Abstract

objectivesAsthma is the most prevalent chronic disease among children enrolled in Medicaid. This study measured real-world adherence and outcomes after an initial prescription for inhaled corticosteroid therapy in a multi-state Medicaid population.

methodsWe conducted a retrospective study among Medicaid-enrolled children aged 5-12 years with asthma in 14 southern states using 2007 Medicaid Analytic eXtract file claims data to assess adherence and outcomes over the 3 months following an initial prescription drug claim for inhaled corticosteroids (ICS-Rx). Adherence was measured by the long-term controller-to-total asthma drug claims ratio.

resultsOnly one-third of children (33.4%) with an initial ICS-Rx achieved a controller-to-total drug ratio >0.5 over the next 90 days. Children for whom long-term control drugs represented less than half of their total asthma drug claims had a 21% higher risk of emergency department (ED) visit (adjusted odds ratio (AOR) 1.21 [95% CI 1.14, 1.27]), and a 70% higher risk of hospital admission (AOR 1.70 [95% CI 1.45, 1.98]) than those with a controller-to-total asthma drug ratio >0.5.

conclusionReal-world adherence to long-term controller medications is quite low in this racially diverse, low-income segment of the population, despite Medicaid coverage of medications. Adherence to long-term controller therapy had a measurable impact on real-world outcomes. Medicaid programs are a potential surveillance system for both medication adherence and ED utilization.

Indexed as

Drug MonitoringAdministration, InhalationAdrenal Cortex HormonesAnti-Asthmatic AgentsAsthmaChildChild, PreschoolChi-Square DistributionCohort StudiesEmergency Service, HospitalFemaleHumansMaleMedicaidRetrospective StudiesRural PopulationAdrenal Cortex HormonesAnti-Asthmatic Agents

Identifiers

PMID23734973
PMCPMC4017346
OpenAlexW2055604713

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.