Evidence map›Paper›PMID 23734858›Full record

Trial reportAddiction (Abingdon, England)2013

Comparison of behavioral treatment conditions in buprenorphine maintenance.

Walter Ling, Maureen Hillhouse, Alfonso Ang, Jessica Jenkins, Jacqueline Fahey

5 registry-linked trialsOpen access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Addiction (Abingdon, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 60 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 10 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04257214 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine

TypeinterventionalSponsorPhiladelphia College of Osteopathic MedicineRan2020 to 2026Enrolled340ConditionsOpioid Use DisorderArmsPsychosocial treatment
NCT04650386 nacompletednot on this mapstarted 2020, after this paper: background citation

Enhancing Office-based Buprenorphine Treatment: An Adaptive Psychosocial Approach

TypeinterventionalSponsorPublic Health Management CorporationRan2020 to 2024Enrolled125ConditionsOpioid-use DisorderArmsPsychosocial support determined by adaptive treatment algorithm
NCT04927143 narecruitingnot on this mapstarted 2021, after this paper: background citation

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

TypeinterventionalSponsorWake Forest University Health SciencesRan2021 to 2026Enrolled600ConditionsOpioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine UseArmsApp-Based Contingency Management, Sham Control
NCT06008769 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Cognitive-Behavioral Therapy for Opioid Use Disorder: A Manualized Pilot Study

TypeinterventionalSponsorPhiladelphia College of Osteopathic MedicineRan2023 to 2024Enrolled20ConditionsOpioid Use DisorderArms12 Week Manualized Cognitive-Behavioral Therapy Intervention
NCT06359340 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Identifying Optimal Psychosocial Interventions for Patients Receiving Office-Based Buprenorphine

TypeinterventionalSponsorPublic Health Management CorporationRan2020 to 2026Enrolled440ConditionsOpioid-use DisorderArmsPsychosocial treatment
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 10 syntheses or guidelines pooled it, 125 citations in OpenAlex.

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  4. A Systematic Review of Noninvasive Brain Stimulation for Opioid Use Disorder.Neuromodulation : journal of the International Neuromodulation Society · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Walter LingIntegrated Substance Abuse Programs, University of California, Los Angeles, CA, USA.
Maureen Hillhouse
Alfonso Ang
Jessica Jenkins
Jacqueline Fahey
OASIS Clinic · USUniversity of California, Los Angeles · US

Funding

Optimizing Outcomes Using Suboxone for Opiate Dependence (R01 DA 020210-01)R01DA020210 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LING, WALTER NMN · 2006 to 2010
$2.5M
NIDA NIH HHS DA020210NIDA NIH HHS R01 DA020210
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe Controlled Substances Act requires physicians in the United States to provide or refer to behavioral treatment when treating opioid-dependent individuals with buprenorphine; however, no research has examined the combination of buprenorphine with different types of behavioral treatments. This randomized controlled trial compared the effectiveness of four behavioral treatment conditions provided with buprenorphine and medical management (MM) for the treatment of opioid dependence.

designAfter a 2-week buprenorphine induction/stabilization phase, participants were randomized to one of four behavioral treatment conditions provided for 16 weeks: cognitive behavioral therapy (CBT = 53); contingency management (CM = 49); both CBT and CM (CBT + CM = 49); and no additional behavioral treatment (NT = 51).

settingStudy activities occurred at an out-patient clinical research center in Los Angeles, California, USA.

participantsIncluded were 202 male and female opioid-dependent participants. MEASUREMENTS: Primary outcome was opioid use, measured as a proportion of opioid-negative urine results over the number of tests possible. Secondary outcomes include retention, withdrawal symptoms, craving, other drug use and adverse events.

findingsNo group differences in opioid use were found for the behavioral treatment phase (χ2  = 1.25, P = 0.75), for a second medication-only treatment phase, or at weeks 40 and 52 follow-ups. Analyses revealed no differences across groups for any secondary outcome.

conclusionThere remains no clear evidence that cognitive behavioural therapy and contingency management reduce opiate use when added to buprenorphine and medical management in opiate users seeking treatment.

Indexed as

Cognitive Behavioral TherapyAdultAnalgesics, OpioidBuprenorphineCombined Modality TherapyFemaleHumansLos AngelesMaleMiddle AgedNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersOutpatientsSubstance Withdrawal SyndromeTreatment OutcomeAnalgesics, OpioidBuprenorphineNarcotic AntagonistsBehavioral treatmentbuprenorphinecognitive behavioral therapycontingency managementmedication managementopiatesopioids

Identifiers

PMID23734858
PMCPMC3866908
OpenAlexW2153599479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.