ArticleLipids in health and disease2013
Total cholesterol and lipoprotein composition are associated with dry eye disease in Korean women.
Article in Lipids in health and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- The Impact of a High-Fat Diet on Eye Health.Nutrients · 2025Pooled it
- Association between dyslipidaemia and dry eye disease: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Systemic Conditions Associated with Severity of Dry Eye Signs and Symptoms in the Dry Eye Assessment and Management Study.Ophthalmology · 2021Trial
- Assessment of the aggregate index of systemic inflammation in dyslipidemia with dry eye disease: a retrospective case-control.Frontiers in ophthalmology · 2026Article
- HDL May Improve Ocular Tear Film Stability in Patients with Gastric Bypass: A Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Association between Disorders of Lipid Metabolism and Oculopathy: An Overview.International journal of medical sciences · 2025Review
- Association between statin use and dry eye disease in patients with hyperlipidemia: A population-based retrospective cohort study.Clinical and translational science · 2024Article
- Article
- Investigating Factors Influencing the National Cancer Screening Program among Older Individuals in Republic of Korea-Data from the Korea National Health and Nutrition Examination Survey VIII.Healthcare (Basel, Switzerland) · 2024Article
- Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study.Lipids in health and disease · 2024Article
- Impact of Dyslipidemia on Tear Film and Meibomian Gland Dysfunction: A Cross-Sectional Study of the Interplay between Serum Lipid Profile and Ocular Surface Health.Journal of ophthalmology · 2024Article
- Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review.Journal of clinical medicine · 2023Review
- Article
- Genetic evidence implicating circulating lipids and lipid drug targets in pterygium.Computational and structural biotechnology journal · 2023Article
- Induction of meibocyte differentiation by three-dimensional, matrigel culture of immortalized human meibomian gland epithelial cells to form acinar organoids.The ocular surface · 2022Article
- Effect of Gardenia Pomace Supplementation on Growth Performance, Blood Metabolites, Immune and Antioxidant Indices, and Meat Quality in Xiangcun Pigs.Animals : an open access journal from MDPI · 2022Article
- Associations between Biomarkers of Metal Exposure and Dry Eye Metrics in Shipyard Welders: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Differential effects of dietary cholesterol and triglycerides on the lipid homeostasis in Meibomian glands.The Journal of steroid biochemistry and molecular biology · 2021Article
- The protective roles of clusterin in ocular diseases caused by obesity and diabetes mellitus type 2.Molecular biology reports · 2021Review
- Dry eye and percentage of body fat: a cross-sectional prospective study.International ophthalmology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to determine the relationship between dyslipidemia and dry eye disease (DED) in a Korean population.
methodsThis population-based study enrolled 5,627 adults (aged >19 years) who were participating in the first year of the fifth annual Korea National Health and Nutrition Examination Survey from 2010 to 2011. Clinically diagnosed DED and its symptoms were surveyed, and biochemical blood analysis data were collected. Dyslipidemia was defined as any of the following: hypercholesterolemia (total cholesterol > 200 mg/dL), hypertriglyceridemia (triglyceride > 150 mg/dL), low levels of high-density lipoprotein (<40 mg/dL), or high levels of low-density lipoprotein (>100 mg/dL).
resultsAfter adjusting for demographics (age and body mass index), lifestyle (smoking, drinking, exercise, and residential district), and medical factors (diabetes, hypertension, previous ophthalmic surgery, menopause, and rheumatologic disease), elevated serum cholesterol level was found to be associated with increased likelihood of DED (odds ratio, 1.77; 95% confidence interval, 1.127-2.78) in women.
conclusionsDED in a Korean population was found to be associated with high serum cholesterol levelsThe results of this study highlight the significance of eye examinations and independent lipid profile monitoring in patients with dyslipidemia because of its possible correlation with DED progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.