ArticlePloS one2013
Uniparental markers in Italy reveal a sex-biased genetic structure and different historical strata.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 84 citations in OpenAlex.
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- Contrasting Maternal, Paternal, and Biparental Ancestry of Populations From the Caribbean Coast of Colombia.American journal of biological anthropology · 2026Article
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- Helena's Many Daughters: More Mitogenome Diversity behind the Most Common West Eurasian mtDNA Control Region Haplotype in an Extended Italian Population Sample.International journal of molecular sciences · 2022Article
- The Ancestry of Eastern Paraguay: A Typical South American Profile with a Unique Pattern of Admixture.Genes · 2021Article
- Through 40,000 years of human presence in Southern Europe: the Italian case study.Human genetics · 2021Review
- Y-chromosome variability and genetic history of Commons from Northern Italy.American journal of physical anthropology · 2021Article
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- Genetic history of Calabrian Greeks reveals ancient events and long term isolation in the Aspromonte area of Southern Italy.Scientific reports · 2021Article
- The mitogenome portrait of Umbria in Central Italy as depicted by contemporary inhabitants and pre-Roman remains.Scientific reports · 2020Article
- Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans.BMC biology · 2020Article
- Rare human mitochondrial HV lineages spread from the Near East and Caucasus during post-LGM and Neolithic expansions.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 3 countries.
Funding
Abstract
Located in the center of the Mediterranean landscape and with an extensive coastal line, the territory of what is today Italy has played an important role in the history of human settlements and movements of Southern Europe and the Mediterranean Basin. Populated since Paleolithic times, the complexity of human movements during the Neolithic, the Metal Ages and the most recent history of the two last millennia (involving the overlapping of different cultural and demic strata) has shaped the pattern of the modern Italian genetic structure. With the aim of disentangling this pattern and understanding which processes more importantly shaped the distribution of diversity, we have analyzed the uniparentally-inherited markers in ∼900 individuals from an extensive sampling across the Italian peninsula, Sardinia and Sicily. Spatial PCAs and DAPCs revealed a sex-biased pattern indicating different demographic histories for males and females. Besides the genetic outlier position of Sardinians, a North West-South East Y-chromosome structure is found in continental Italy. Such structure is in agreement with recent archeological syntheses indicating two independent and parallel processes of Neolithisation. In addition, date estimates pinpoint the importance of the cultural and demographic events during the late Neolithic and Metal Ages. On the other hand, mitochondrial diversity is distributed more homogeneously in agreement with older population events that might be related to the presence of an Italian Refugium during the last glacial period in Europe.
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