ArticleGenetics2013
Testing for the footprint of sexually antagonistic polymorphisms in the pseudoautosomal region of a plant sex chromosome pair.
Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 57 citations in OpenAlex.
- Evolutionary dynamics of enlarged neo-sex chromosomes and novel pseudoautosomal regions in Sylvioidea songbirds.Communications biology · 2026Article
- Genome assemblies of the liverwort Blasia pusilla uncover a well-defined pseudoautosomal region on homomorphic UV sex chromosomes.Genome biology · 2026Article
- Evolution and regulation of animal sex chromosomes.Nature reviews. Genetics · 2025Review
- Improved assembly of the Pungitius pungitius reference genome.G3 (Bethesda, Md.) · 2024Article
- The roles of gene duplications in the dynamics of evolutionary conflicts.Proceedings. Biological sciences · 2024Review
- Evolutionary History of the Poecilia picta Sex Chromosomes.Genome biology and evolution · 2023Article
- Independent Evolution of Sex Chromosomes and Male Pregnancy-Related Genes in Two Seahorse Species.Molecular biology and evolution · 2023Article
- Recent expansion of the non-recombining sex-linked region on Silene latifolia sex chromosomes.Journal of evolutionary biology · 2022Article
- Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes.Genome biology · 2022Article
- Detecting sex-linked genes using genotyped individuals sampled in natural populations.Genetics · 2021Article
- Review
- The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics.Evolution letters · 2020Article
- The Location of the Pseudoautosomal Boundary inGenes · 2020Article
- Sex Chromosome Evolution in Muscid Flies.G3 (Bethesda, Md.) · 2020Article
- Repeated translocation of a gene cassette drives sex-chromosome turnover in strawberries.PLoS biology · 2018Article
- Article
- Review
- Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture.Evolution letters · 2018Article
- Population genetics of sexual conflict in the genomic era.Nature reviews. Genetics · 2017Review
- Recent Sex Chromosome Divergence despite Ancient Dioecy in the Willow Salix viminalis.Molecular biology and evolution · 2017Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
The existence of sexually antagonistic (SA) polymorphism is widely considered the most likely explanation for the evolution of suppressed recombination of sex chromosome pairs. This explanation is largely untested empirically, and no such polymorphisms have been identified, other than in fish, where no evidence directly implicates these genes in events causing loss of recombination. We tested for the presence of loci with SA polymorphism in the plant Silene latifolia, which is dioecious (with separate male and female individuals) and has a pair of highly heteromorphic sex chromosomes, with XY males. Suppressed recombination between much of the Y and X sex chromosomes evolved in several steps, and the results in Bergero et al. (2013) show that it is still ongoing in the recombining or pseudoautosomal, regions (PARs) of these chromosomes. We used molecular evolutionary approaches to test for the footprints of SA polymorphisms, based on sequence diversity levels in S. latifolia PAR genes identified by genetic mapping. Nucleotide diversity is high for at least four of six PAR genes identified, and our data suggest the existence of polymorphisms maintained by balancing selection in this genome region, since molecular evolutionary (HKA) tests exclude an elevated mutation rate, and other tests also suggest balancing selection. The presence of sexually antagonistic alleles at a locus or loci in the PAR is suggested by the very different X and Y chromosome allele frequencies for at least one PAR gene.
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