Evidence map›Paper›PMID 23733379›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2013

Factors associated with discontinuation of bupropion and counseling among African American light smokers in a randomized clinical trial.

Nicole L Nollen, Matthew S Mayo, Jasjit S Ahluwalia, Rachel F Tyndale, Neal L Benowitz, Babalola Faseru, Taneisha S Buchanan, Lisa Sanderson Cox

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Correlates of Adherence to Varenicline Among HIV+ Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Trial
  7. Perceived treatment assignment and smoking cessation in a clinical trial of bupropion versus placebo.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Trial
  8. Article
  9. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023
    Review
  10. Adherence to Pharmacological Smoking Cessation Interventions: A Literature Review and Synthesis of Correlates and Barriers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Nicole L NollenDepartment of Preventive Medicine and Public Health, University of Kansas School of Medicine, 3901 Rainbow Boulevard, Mail Stop 1030, Kansas City, KS, 66160, USA, nnollen@kumc.edu.
Matthew S Mayo
Jasjit S Ahluwalia
Rachel F Tyndale
Neal L Benowitz
Babalola Faseru
Taneisha S Buchanan
Lisa Sanderson Cox
The University of Kansas Cancer Center · USUniversity of Kansas · USUniversity of Minnesota Medical Center · USCentre for Addiction and Mental Health · CAUniversity of California, San Francisco · US

Funding

Research Support CoreP30DA012393 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JACOB, PEYTON, JONES, REESE T. · 1999 to 2024
$17.1M
The Center for Health Disparities Research, Engagement, and Training (CeHDRET)P60MD003422 · NIMHD · UNIVERSITY OF MINNESOTA · PI EVERSON-ROSE, SUSAN A. · 2009 to 2013
$6.1M
Helping African American Light Smokers QuitR01CA091912 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI COX, LISA SANDERSON · 2001 to 2010
$5.6M
NCI NIH HHS CA 091912NCI NIH HHS R01 CA091912NIDA NIH HHS P30 DA012393NIMHD NIH HHS 1P60MD003422NIMHD NIH HHS P60 MD003422
6 · The paper itself

Abstract

backgroundAfrican Americans are at risk of inadequate adherence to smoking cessation treatment, yet little is known about what leads to treatment discontinuation. PURPOSE: The purpose of this study was to examine the factors associated with discontinuation of treatment in African American light smokers (≤10 cigarettes per day).

methodsBupropion plasma levels and counseling attendance were measured among 540 African American light smokers in a placebo-controlled randomized trial of bupropion.

resultsBy week 3, 28.0 % of subjects in the bupropion arm had discontinued bupropion, and only moderate associations were found between the plasma levels and self-reported bupropion use (r s = 0.38). By week 16, 36.9 % of all subjects had discontinued counseling. Males had greater odds of discontinuing medication (OR = 2.02, 95% CI = 1.10-3.71, p = 0.02), and older adults had lower odds of discontinuing counseling (OR = 0.96, 95% CI = 0.94-0.97, p < 0.0001).

conclusionsBupropion and smoking cessation counseling are underutilized even when provided within the context of a randomized trial. Future research is needed to examine strategies for improving treatment utilization among African American smokers.

Indexed as

CounselingAgingBlack or African AmericanBupropionDelayed-Action PreparationsFemaleHumansMaleMiddle AgedPatient ComplianceSex CharacteristicsSmoking CessationBupropionDelayed-Action Preparations

Identifiers

PMID23733379
PMCPMC3815499
OpenAlexW2056795229

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.