Evidence map›Paper›PMID 23733252›Full record

ArticleFamilial cancer2014

Mammographic surveillance in women aged 35-39 at enhanced familial risk of breast cancer (FH02).

D G Evans, S Thomas, J Caunt, L Roberts, A Howell, M Wilson, R Fox, D M Sibbering, S Moss, M G Wallis and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Familial cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Targeting breast cancer outcomes-what about the primary relatives?Molecular genetics & genomic medicine · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

D G EvansGenesis Breast Cancer Prevention Centre, University Hospital of South Manchester NHS Trust, Wythenshawe, Manchester, M23 9LT, UK, gareth.evans@cmft.nhs.uk.
S Thomas
J Caunt
L Roberts
A Howell
M Wilson
R Fox
D M Sibbering
S Moss
M G Wallis
D M Eccles
FH02 study group
S Duffy
Wythenshawe Hospital · GBCancer Research UK · GBRoyal Derby Hospital · GBUniversity of Manchester · GBSouthampton General Hospital · GB

Funding

Department of Health NF-SI-0509-10214
6 · The paper itself

Abstract

Although there have been encouraging recent studies showing a potential benefit from annual mammography in women aged 40-49 years of age with an elevated breast cancer risk due to family history there is little evidence of efficacy in women aged <40 years of age. A prospective study (FH02) has been developed to assess the efficacy of mammography screening in women aged 35-39 years of age with a lifetime breast cancer risk of ≥ 17 % who are not receiving MRI screening. Retrospective analyses from five centres with robust recall systems identified 47 breast cancers (n = 12 in situ) with an interval cancer rate of 15/47 (32%). Invasive tumour size, lymph node status and current vital status were all significantly better than in two control groups of unscreened women (including those with a family history) recruited to the POSH study. Further evaluation of the prospective arm of FH02 is required to assess the potential added value of digital mammography and the cancer incidence rates in moderate and high risk women in order to inform cost effectiveness analyses.

Indexed as

AdultBreast NeoplasmsFemaleGenetic Predisposition to DiseaseHumansMammographyMass ScreeningProspective StudiesRisk FactorsUnited Kingdom

Identifiers

PMID23733252
OpenAlexW1975123333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.