Evidence map›Paper›PMID 23733150›Full record

ArticleEuropean child & adolescent psychiatry2014

Association between ADHD drug use and injuries among children and adolescents.

Els van den Ban, Patrick Souverein, Willemijn Meijer, Herman van Engeland, Hanna Swaab, Toine Egberts, Eibert Heerdink

Abstract read
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In one paragraph

Article in European child & adolescent psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Stimulant Medications and Bone Health.Current osteoporosis reports · 2026
    Review
  7. Article
  8. Article
  9. Attention-Deficit/Hyperactivity Disorder Medication and Unintentional Injuries in Children and Adolescents.Journal of the American Academy of Child and Adolescent Psychiatry · 2020
    Article
  10. Dog bite injuries in the USA: prevalence, correlates and recent trends.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2019
    Article
  11. Observational
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Gender and injuries predict stimulant medication use.Journal of child and adolescent psychopharmacology · 2014
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Els van den BanYouth Division, Altrecht, Institute for Mental Health, Nieuwe Houtenseweg 2, 3524 SH, Utrecht, The Netherlands, e.van.den.ban@altrecht.nl.
Patrick Souverein
Willemijn Meijer
Herman van Engeland
Hanna Swaab
Toine Egberts
Eibert Heerdink

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the association between attention deficit hyperactivity disorder (ADHD) drug use and the incidence of hospitalization due to injuries. A random sample of 150,000 persons (0-18 years) was obtained from the Dutch PHARMO record linkage system. An ADHD medication cohort as well as an up to six age/sex/index date sampled control cohort with no history of ADHD drug use was formed. Differences in incidence of hospitalization due to injuries were stratified for age and sex and compared prior, during and after exposure on ADHD drugs. The overall incidence of hospital admissions for injuries was two times higher in the ADHD medication cohort [incidence rate ratios (IRR) 2.2 (95 % CI 1.6-2.9)]. The incidence rate for injuries during exposure to ADHD drugs was lower in the exposed period compared to the period prior to ADHD drug use, although the difference was not statistically significant [IRR 0.68 (95 % CI 0.29-1.60)]. The relative risk for injuries was almost five times higher in the ADHD medication cohort among those who concomitantly used other psychotropics [IRR 4.8 (95 % CI 1.4-16.9)]. Risk for injuries was highest in 12-18 years olds. Children and adolescents using ADHD medication showed a twofold risk for hospital admissions for injuries. ADHD drug use might diminish the increased injury risk, but still overall risk is higher than in age/sex sampled children and adolescents without treatment with ADHD drugs. Use of ADHD and concomitant psychotropics increases the risk for injuries compared to only ADHD drug use.

Indexed as

AdolescentAttention Deficit Disorder with HyperactivityCase-Control StudiesChildChild, PreschoolFemaleHospitalizationHumansIncidenceInfantInfant, NewbornMaleNetherlandsPsychotropic DrugsRegression AnalysisRisk FactorsPsychotropic Drugs

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.