Evidence map›Paper›PMID 23732930›Full record

ArticleArchives of virology2013

A cilevirus infects ornamental hibiscus in Hawaii.

Michael J Melzer, Nelson Simbajon, James Carillo, Wayne B Borth, Juliana Freitas-Astúa, Elliot W Kitajima, Kabi R Neupane, John S Hu

Open access · greenAbstract read
In one paragraph

Article in Archives of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Circulative Transmission of Cileviruses inFrontiers in microbiology · 2022
    Article
  7. Exploring the therapeutic potential ofSaudi journal of biological sciences · 2021
    Article
  8. Article
  9. Article
  10. A Virus InfectingFrontiers in microbiology · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Pest categorisation of Citrus leprosis viruses.EFSA journal. European Food Safety Authority · 2017
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Michael J MelzerDepartment of Plant and Environmental Protection Sciences, University of Hawaii, 3190 Maile Way, St. John 310, Honolulu, HI, 96822, USA, melzer@hawaii.edu.
Nelson Simbajon
James Carillo
Wayne B Borth
Juliana Freitas-Astúa
Elliot W Kitajima
Kabi R Neupane
John S Hu
University of Hawaii System · USUniversity of Hawaiʻi at Mānoa · USBrazilian Agricultural Research Corporation · BRUniversidade de São Paulo · BR

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
USING EEG COMPLEXITY AND HIGH PERFORMANCE COMPUTING TO PROFILE SLEEPP20RR016467 · NCRR · UNIVERSITY OF HAWAII AT MANOA · PI HOLMES, ERIC · 2001 to 2011
$24.5M
NCRR NIH HHS 5P20RR016467-11NCRR NIH HHS P20 RR016467NIGMS NIH HHS 8P20GM103466-11NIGMS NIH HHS P20 GM103466
6 · The paper itself

Abstract

The complete nucleotide sequence of a virus infecting ornamental hibiscus (Hibiscus sp.) in Hawaii with symptoms of green ringspots on senescing leaves was determined from double-stranded RNA isolated from symptomatic tissue. Excluding polyadenylated regions at the 3' termini, the bipartite RNA genome was 8748 and 5019 nt in length for RNA1 and RNA2, respectively. The genome organization was typical of a cilevirus: RNA1 encoded a large replication-associated protein with methyltransferase, protease, helicase and RNA-dependent RNA polymerase domains as well as a 29-kDa protein of unknown function. RNA2 possessed five open reading frames that potentially encoded proteins with molecular masses of 15, 7, 62, 32, and 24 kDa. The 32-kDa protein is homologous to 3A movement proteins of RNA viruses; the other proteins are of unknown function. A proteome comparison revealed that this virus was 92 % identical to citrus leprosis virus cytoplasmic type 2 (CiLV-C2), a recently characterized cilevirus infecting citrus with leprosis-like symptoms in Colombia. The high sequence similarity suggests that the virus described in this study could be a strain of CiLV-C2, but since the new genus Cilevirus does not have species demarcation criteria established at present, the classification of this virus infecting hibiscus is open to interpretation. This study represents the first documented case of a cilevirus established in the United States and provides insight into the diversity within the genus Cilevirus.

Indexed as

Genome, ViralBase SequenceCitrusHawaiiHibiscusMolecular Sequence DataOpen Reading FramesPlant DiseasesPlant LeavesRNA, Double-StrandedRNA, ViralRNA VirusesSequence Analysis, DNASpecies SpecificityViral ProteinsRNA, Double-StrandedRNA, ViralViral Proteins

Identifiers

PMID23732930
PMCPMC3812299
OpenAlexW2042360511

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.